Ayaki Masahiko, Kawashima Motoko, Negishi Kazuno, Tsubota Kazuo
Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Neuropsychiatr Dis Treat. 2015 Mar 31;11:889-94. doi: 10.2147/NDT.S81515. eCollection 2015.
We aimed to explore the prevalence of probable sleep and mood disorders in eye clinic visitors.
This was a cross-sectional study. The participants were outpatients at six eye clinics from January through March, 2014. Outpatients were invited to complete a questionnaire containing the Pittsburgh Sleep Quality Index (PSQI) and Hospital Anxiety and Depression Scale (HADS). A final diagnosis was made, and patients were classified into six diagnostic groups. The main outcome measures were the scores of the PSQI and HADS among the diagnostic groups.
A total 1,000 outpatients participated, and 730 patients (mean age 59.5±19.0 years; 487 females) were analyzed after exclusion of children and patients diagnosed with healthy eyes, acute injury, or unilateral pseudophakia. The mean PSQI and HADS scores across all patients were 5.3±3.1 and 9.2±6.2, respectively. For the diagnostic groups, the mean PSQI and HADS scores, respectively, were 5.7±3.3 and 10.2±6.0 for dry eye (n=247), 5.4±3.2 and 9.2±5.7 for bilateral cataracts (n=159), 5.3±3.3 and 8.0±5.3 for bilateral pseudophakia (n=99), and, 5.0±3.1 and 9.8±6.6 for glaucoma (n=109). Overall, 37.3% of patients were poor sleepers (PSQI ≥6), and 45.5% had possible mood disorders (HADS ≥10). Stepwise regression analysis revealed that the PSQI and HADS scores were significantly correlated with both age (P<0.05) and the presence of dry eye (P<0.05).
The prevalence of sleep and mood disorders was significantly higher in patients with dry eye. The present results suggest consultation-liaison psychiatry services may be beneficial among eye disease patients.
我们旨在探究眼科门诊患者中可能存在的睡眠和情绪障碍的患病率。
这是一项横断面研究。研究对象为2014年1月至3月期间六家眼科门诊的门诊患者。邀请门诊患者完成一份包含匹兹堡睡眠质量指数（PSQI）和医院焦虑抑郁量表（HADS）的问卷。做出最终诊断，并将患者分为六个诊断组。主要结局指标为各诊断组的PSQI和HADS评分。
共有1000名门诊患者参与，排除儿童以及被诊断为眼睛健康、急性损伤或单侧人工晶状体植入的患者后，对730名患者（平均年龄59.5±19.0岁；487名女性）进行了分析。所有患者的PSQI和HADS平均得分分别为5.3±3.1和9.2±6.2。对于各诊断组，干眼症患者（n=247）的PSQI和HADS平均得分分别为5.7±3.3和10.2±6.0，双侧白内障患者（n=159）分别为5.4±3.2和9.2±5.7，双侧人工晶状体植入患者（n=99）分别为5.3±3.3和8.0±5.3，青光眼患者（n=109）分别为5.0±3.1和9.8±6.6。总体而言，37.3%的患者睡眠质量差（PSQI≥6），45.5%的患者可能存在情绪障碍（HADS≥10）。逐步回归分析显示，PSQI和HADS评分与年龄（P<0.05）和干眼症的存在（P<0.05）均显著相关。
干眼症患者中睡眠和情绪障碍的患病率显著更高。目前的结果表明，会诊联络精神病学服务可能对眼病患者有益。
