2012年伊朗北部戈勒斯坦省戈尔甘市孕妇弓形虫感染血清阳性率
Seroprevalence of Toxoplasma gondii Infections in Pregnant Women in Gorgan City, Golestan Province, Northern Iran-2012.
作者信息
Sharbatkhori Mitra, Dadi Moghaddam Yusef, Pagheh Abdol Sattar, Mohammadi Rasool, Hedayat Mofidi Haleh, Shojaee Saeedeh
机构信息
Department of Medical Parasitology & Mycology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran ; Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Social Security Organization, Gonbad, Iran.
出版信息
Iran J Parasitol. 2014 Apr-Jun;9(2):181-7.
BACKGROUND
Toxoplasma gondii is one of the most prevalent parasites of human and warm- blooded animals. Toxoplasmosis is important especially in two groups: pregnant women and immunocompromised patients. If women acquire the primary infection during the pregnancy, it would be life threatening or remains severe disorders for the fetus. This study was performed to evaluate the seroprevalence of T. gondii infection in pregnant women referred to Health Center in Gorgan City, Golestan Province, northern Iran.
METHODS
Serum samples were collected from pregnant women referred to Health Center in Gorgan City, south eastern Caspian Sea. Anti- Toxoplasma IgG and IgM antibodies were determined by commercially ELISA kits and the relation of infection with socio-demographic and risk factors such as age, education, occupation, cat ownership, soil contact and some other factors was studied.
RESULTS
From 555 tested sera of pregnant women referred to Health Center in Gorgan, 39.8% had IgG antibodies against T. gondii and 3.4% were positive for IgM antibodies. A significant correlation was seen between T. gondii infection with age and soil contact.
CONCLUSION
About 60% of pregnant women in Gorgan City are seronegative against T. gondii, so they should considered as at risk persons.
背景
弓形虫是人类和温血动物中最常见的寄生虫之一。弓形虫病在两类人群中尤为重要：孕妇和免疫功能低下的患者。如果女性在孕期发生原发性感染，可能会危及生命或导致胎儿出现严重疾病。本研究旨在评估转诊至伊朗北部戈勒斯坦省戈尔甘市健康中心的孕妇中弓形虫感染的血清流行率。
方法
收集转诊至里海东南部戈尔甘市健康中心的孕妇的血清样本。采用商用ELISA试剂盒检测抗弓形虫IgG和IgM抗体，并研究感染与社会人口统计学及年龄、教育程度、职业、养猫、接触土壤等危险因素之间的关系。
结果
在转诊至戈尔甘市健康中心的555名孕妇的检测血清中，39.8%的人有抗弓形虫IgG抗体，3.4%的人IgM抗体呈阳性。弓形虫感染与年龄和接触土壤之间存在显著相关性。
结论
戈尔甘市约60%的孕妇弓形虫血清学检测呈阴性，因此应将她们视为高危人群。
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