Long Parma Dorothy, Hughes Daniel C, Ghosh Sagar, Li Rong, Treviño-Whitaker Rose A, Ogden Susan M, Ramirez Amelie G
Department of Epidemiology and Biostatistics, Institute for Health Promotion Research, University of Texas Health Science Center at San Antonio, 7411 John Smith Drive Suite 1000, San Antonio, TX USA.
SRA International, Inc., Fairfax, VA USA.
Springerplus. 2015 Mar 26;4:143. doi: 10.1186/s40064-015-0912-z. eCollection 2015.
Yoga-based exercise has proven to be beneficial for practitioners, including cancer survivors. This study reports on the effect on inflammatory biological markers for 20 breast cancer survivors who participated in a six-month yoga-based (YE) exercise program. Results are compared to a comprehensive exercise (CE) program group and a comparison (C) exercise group who chose their own exercises. "Pre" and "post" assessments included measures of anthropometrics, cardiorespiratory capacity, and inflammatory markers interleukin 6 (IL-6), interleukin 8 (IL-8), tumor necrosis factor alpha (TNFα) and C-reactive protein (CRP). Descriptive statistics, effect size (d), and dependent sample 't' tests for all outcome measures were calculated for the YE group. Significant improvements were seen in decreased % body fat, (-3.00%, d = -0.44, p = <.001) but not in cardiorespiratory capacity or in inflammatory serum markers. To compare YE outcomes with the other two groups, a one-way analysis of co-variance (ANCOVA) was used, controlling for age, BMI, cardiorespiratory capacity and serum marker baseline values. We found no differences between groups. Moreover, we did not see significant changes in any inflammatory marker for any group. Our results support the effectiveness of yoga-based exercise modified for breast cancer survivors for improving body composition. Larger studies are needed to determine if there are significant changes in inflammatory serum markers as a result of specific exercise modalities.
事实证明，基于瑜伽的运动对包括癌症幸存者在内的练习者有益。本研究报告了20名参加了为期六个月的基于瑜伽（YE）运动项目的乳腺癌幸存者的炎症生物标志物变化情况。研究结果与一个综合运动（CE）项目组以及一个自行选择运动方式的对照（C）运动组进行了比较。“前”和“后”评估包括人体测量学指标、心肺功能以及炎症标志物白细胞介素6（IL-6）、白细胞介素8（IL-8）、肿瘤坏死因子α（TNFα）和C反应蛋白（CRP）的测量。对YE组的所有结果指标计算了描述性统计量、效应大小（d）和相关样本t检验。结果显示，体脂百分比显著下降（-3.00%，d = -0.44，p = <.001），但心肺功能或炎症血清标志物方面没有变化。为了将YE组的结果与其他两组进行比较，采用了单因素协方差分析（ANCOVA），并对年龄、体重指数、心肺功能和血清标志物基线值进行了控制。我们发现各组之间没有差异。此外，我们没有观察到任何一组的任何炎症标志物有显著变化。我们的研究结果支持了为乳腺癌幸存者量身定制的基于瑜伽的运动在改善身体成分方面的有效性。需要进行更大规模的研究来确定特定运动方式是否会导致炎症血清标志物发生显著变化。
