Akin Yigit, Gulmez Hakan, Savas Murat, Aykan Serdar, Onder Ozde, Yucel Selcuk
Department of Urology, Harran University School of Medicine, 63100, Sanliurfa, Turkey.
Department of Family Medicine, Public Health Institute, Konya, Turkey.
Wien Klin Wochenschr. 2016 Dec;128(Suppl 8):581-586. doi: 10.1007/s00508-015-0725-7. Epub 2015 Apr 9.
To investigate relationship between overactive bladder (OAB) and metabolic syndrome (MtS) by using neck circumference (NC).
In retrospective view of prospective collected data, 204 women with or without OAB were enrolled into study, between August 2012 and December 2013. All patients were administered OAB validated questionnaires (OAB-V8) and whose score was > 8 were accepted as OAB. Patients were divided into two groups and group 1 consisted of patients with OAB, group 2 consisted of patients without OAB. Demographic data with anthropometric measurements and blood analyses were recorded. Statistical analyses including receiver operating characteristic (ROC) curves were performed; statistically significant p was < 0.05.
Mean age was 41.06 ± 9.78 years. There were 115 (56.4 %) patients in group 1, and 89 (43.6 %) patients in group 2. OAB-V8 scores were significant higher in group 1 than group 2 (p < 0.001). Waist circumference (WC) and NC measurements were statistical significant longer in group 1 than group 2 (p < 0.001). In multivariate logistic regression analyses age, body mass index, MtS, WC, and NC were statistical significant associated with OAB. In ROC curves, area under the curve (AUC) was 0.72 cm for relationship between OAB and WC (p < 0.001), and AUC was 0.73 cm for relationship between OAB and NC (p = 0.004). Cut-off NC and WC values for OAB were determined as 35.25 cm and 98.5 cm, respectively.
OAB with metabolic syndrome seems like more common in women than in those without. NC may be a novel indicator for OAB in selected female patients with MtS.
通过颈围（NC）研究膀胱过度活动症（OAB）与代谢综合征（MtS）之间的关系。
回顾性分析2012年8月至2013年12月前瞻性收集的数据，纳入204例有或无OAB的女性患者。所有患者均接受OAB有效问卷（OAB-V8）评估，得分>8分者被诊断为OAB。患者分为两组，第1组为OAB患者，第2组为无OAB患者。记录人口统计学数据、人体测量数据和血液分析结果。进行包括受试者操作特征（ROC）曲线在内的统计分析；具有统计学意义的p值<0.05。
平均年龄为41.06±9.78岁。第1组有115例（56.4%）患者，第2组有89例（43.6%）患者。第1组的OAB-V8得分显著高于第2组（p<0.001）。第1组的腰围（WC）和颈围测量值在统计学上显著长于第2组（p<0.001）。在多因素逻辑回归分析中，年龄、体重指数、MtS、WC和NC与OAB在统计学上显著相关。在ROC曲线中，OAB与WC之间关系的曲线下面积（AUC）为0.72 cm（p<0.001），OAB与NC之间关系的AUC为0.73 cm（p=0.004）。OAB的颈围和腰围截断值分别确定为35.25 cm和98.5 cm。
患有代谢综合征的OAB在女性中似乎比未患代谢综合征的女性更常见。颈围可能是特定患有MtS的女性患者中OAB的一个新指标。
