Hu Jennifer, Gottlieb Cornelia B, Barajas Daniel J, Barnett Cullen J, Schoenholz Tamera, Sadda SriniVas R
Ophthalmic Surg Lasers Imaging Retina. 2015 Mar;46(3):310-4. doi: 10.3928/23258160-20150323-02.
To assess repeatability and speed of a line-scan ophthalmoscope (LSO) image-based tracking system and compare to the point-scanning approach.
Thirty-five eyes with retinal diseases underwent volume scans using two spectral-domain optical coherence tomography (OCT) devices: a line-scan tracking Cirrus HD-OCT (Carl Zeiss Meditec; Dublin, CA) and point-scan tracking Spectralis HRA+OCT (Heidelberg Engineering, Heidelberg, Germany). Eyes were also imaged on the Cirrus HD-OCT with tracking disabled.
Mean difference in central subfield thickness (CST) between consecutive scans was 2.6 µm for the Cirrus without tracking, 1.7 µm with tracking, and 3.6 µm for the Spectralis. The repeatability standard deviation was 3.0 µm for the Cirrus without tracking, 1.5 µm with tracking, and 4.0 µm for the Spectralis. Coefficient of variation for the CST was 1.1% for the Cirrus without tracking, 0.5% with tracking, and 1.4% for the Spectralis. Mean scan acquisition time was 12.3 ± 6.2 seconds for the Spectralis, 7.8 ± 6.7 for the Cirrus with tracking, and 4.3 ± 0.6 for the Cirrus without tracking.
Real-time LSO image-based retinal tracking appears to improve repeatability of OCT retinal thickness measurements.
评估基于线扫描检眼镜(LSO)图像的跟踪系统的可重复性和速度,并与点扫描方法进行比较。
35只患有视网膜疾病的眼睛使用两种光谱域光学相干断层扫描(OCT)设备进行容积扫描:线扫描跟踪的Cirrus HD-OCT(卡尔蔡司医疗技术公司;加利福尼亚州都柏林)和点扫描跟踪的Spectralis HRA+OCT(海德堡工程公司,德国海德堡)。这些眼睛还在跟踪功能禁用的情况下在Cirrus HD-OCT上进行成像。
对于Cirrus,无跟踪时连续扫描之间的中央子场厚度(CST)平均差异为2.6 µm,有跟踪时为1.7 µm,对于Spectralis为3.6 µm。Cirrus无跟踪时的重复性标准差为3.0 µm,有跟踪时为1.5 µm,Spectralis为4.0 µm。Cirrus无跟踪时CST的变异系数为1.1%,有跟踪时为0.5%,Spectralis为1.4%。Spectralis的平均扫描采集时间为12.3±6.2秒,Cirrus有跟踪时为7.8±6.7秒,Cirrus无跟踪时为4.3±0.6秒。
基于实时LSO图像的视网膜跟踪似乎可提高OCT视网膜厚度测量的可重复性。