Neuroimmunology Clinic, Concord Hospital and University of Sydney, Sydney, New South Wales, Australia.
Department of Neuroinflammation, UCL Institute of Neurology, Queen Square MS Centre, London, UK.
J Neurol Neurosurg Psychiatry. 2015 Dec;86(12):1374-82. doi: 10.1136/jnnp-2014-309649. Epub 2015 Apr 9.
Lesions in the corpus callosum (CC) are important radiological clues to the diagnosis of multiple sclerosis (MS), but may also occur in other neuroinflammatory and non-neuroinflammatory conditions. In this article, we discuss the radiological features of lesions within the CC in MS and other central nervous system inflammatory and acquired demyelinating diseases. An understanding of the appearance and location of lesions in the CC is important not only for accurate diagnosis and treatment of these various conditions, but as it also provides insights into pathogenesis.
胼胝体病变是多发性硬化症(MS)诊断的重要影像学线索,但也可能发生在其他神经炎症和非神经炎症疾病中。本文讨论了 MS 及其他中枢神经系统炎症性和获得性脱髓鞘疾病中胼胝体病变的影像学特征。了解胼胝体病变的外观和位置不仅对这些各种疾病的准确诊断和治疗很重要,而且还可以深入了解发病机制。