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抗菌药物耐药性:一项公共卫生挑战。

Antimicrobial resistance: A public health challenge.

作者信息

Jindal A K, Pandya Kapil, Khan I D

机构信息

Commandant, Military Hospital Nasirabad, C/O 56 APO, India.

DADH, HQ 17 Mtn Div, C/O 99 APO, India.

出版信息

Med J Armed Forces India. 2015 Apr;71(2):178-81. doi: 10.1016/j.mjafi.2014.04.011. Epub 2014 Aug 4.

Abstract

Antimicrobial resistance has become a global concern. Though an evolutionary phenomenon, it is promulgated by faulty human behaviours. It is a growing concern ever since first reported in 1940s. Today, a plethora of newer generation antimicrobials have become ineffective against previously susceptible organisms. This is a huge challenge for health care managers all across the globe, compounded by the "discovery void" in the field of development of new antibiotics. If proper steps are not taken presently, the lurking fear of reaching a therapeutic dead end will become a reality. This paper aims at describing the pandemic of AMR from a public health perspective and suggesting strategies to deal with it in an effective and collaborative manner.

摘要

抗菌药物耐药性已成为全球关注的问题。尽管这是一种进化现象,但却是由错误的人类行为所引发的。自20世纪40年代首次报道以来,它一直是一个日益严重的问题。如今,大量新一代抗菌药物对以前敏感的微生物已不再有效。这对全球的医疗保健管理人员来说是一个巨大的挑战,新抗生素研发领域的“发现空白”更是雪上加霜。如果目前不采取适当措施,对达到治疗死胡同的潜在担忧将成为现实。本文旨在从公共卫生角度描述抗菌药物耐药性的流行情况,并提出以有效和协作方式应对它的策略。

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