Wall Anneli, Borg Jörgen, Palmcrantz Susanne
Department of Rehabilitation Medicine, Danderyd University Hospital Stockholm, Sweden ; Department of Clinical Sciences, Karolinska Institute Stockholm, Sweden.
Front Syst Neurosci. 2015 Mar 25;9:48. doi: 10.3389/fnsys.2015.00048. eCollection 2015.
The aim of this study was to review the literature on clinical applications of the Hybrid Assistive Limb system for gait training.
A systematic literature search was conducted using Web of Science, PubMed, CINAHL and clinicaltrials.gov and additional search was made using reference lists in identified reports. Abstracts were screened, relevant articles were reviewed and subject to quality assessment.
Out of 37 studies, 7 studies fulfilled inclusion criteria. Six studies were single group studies and 1 was an explorative randomized controlled trial. In total, these studies involved 140 participants of whom 118 completed the interventions and 107 used HAL for gait training. Five studies concerned gait training after stroke, 1 after spinal cord injury (SCI) and 1 study after stroke, SCI or other diseases affecting walking ability. Minor and transient side effects occurred but no serious adverse events were reported in the studies. Beneficial effects on gait function variables and independence in walking were observed.
The accumulated findings demonstrate that the HAL system is feasible when used for gait training of patients with lower extremity paresis in a professional setting. Beneficial effects on gait function and independence in walking were observed but data do not allow conclusions. Further controlled studies are recommended.
本研究旨在回顾关于混合辅助肢体系统用于步态训练的临床应用文献。
使用科学网、PubMed、CINAHL和ClinicalTrials.gov进行系统的文献检索，并利用已识别报告中的参考文献列表进行额外检索。对摘要进行筛选，对相关文章进行综述并进行质量评估。
在37项研究中，7项研究符合纳入标准。6项研究为单组研究，1项为探索性随机对照试验。这些研究总共涉及140名参与者，其中118人完成了干预，107人使用混合辅助肢体进行步态训练。5项研究涉及中风后的步态训练，1项涉及脊髓损伤（SCI）后的步态训练，1项研究涉及中风、SCI或其他影响行走能力的疾病后的步态训练。出现了轻微和短暂的副作用，但研究中未报告严重不良事件。观察到对步态功能变量和行走独立性有有益影响。
累积的研究结果表明，在专业环境中，混合辅助肢体系统用于下肢麻痹患者的步态训练是可行的。观察到对步态功能和行走独立性有有益影响，但数据尚不足以得出结论。建议进一步开展对照研究。
