Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore).
College of Science, Sichuan Agricultural University, Ya'an, Sichuan, 625014 (China).
Angew Chem Int Ed Engl. 2015 May 26;54(22):6531-5. doi: 10.1002/anie.201501712. Epub 2015 Apr 13.
Asymmetric reductive Heck reaction of aryl halides is realized in high stereoselectivity. Hydrogen-bond donors, trialkylammonium salts in a glycol solvent, were used to promote halide dissociation from neutral arylpalladium complexes to access cationic, stereoselective pathways.
芳基卤化物的不对称还原 Heck 反应具有高度的立体选择性。氢键供体，三烷基铵盐在二醇溶剂中，被用来促进中性芳基钯配合物中卤化物的离解，以获得阳离子的、立体选择性的途径。
