Abazar Elaheh, Taghian Farzaneh, Mardanian Farahnaz, Forozandeh Dashti
Faculty of Physical Education and Sports Science, Islamic Azad University Khorasghan (Isfahan) Branch, Isfahan, Iran.
Department of Obstetric and Gynecology, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2015 Mar 25;4:68. doi: 10.4103/2277-9175.153892. eCollection 2015.
Polycystic ovary syndrome (PCOS) is one of the most frequent endocrine disorders. The PCOS manifest by hyperandrogenism, hypertension and cholesterol and lipoprotein improper profiles. Changing the life style, e.g. increasing physical activities is the first approach in controlling PCOS.
Twenty-four women affected by polycystic ovary syndrome (PCOS) after medical screening were divided in to two groups: Experimental group (n = 12) and control group (n = 12), with the average age, weight, height, BMI and WHR of 26.87 ± 4.43 years, 75.71 ± 10.65 kg. 159.29 ± 6.44 cm, 29.86 ± 3.22 kg/m(2) and 91.75 ± 5.86 respectively. First the body composition such as BMI, WHR, percent body fat, weight and body fat mass were measured. In fasting blood samples the level of HDL, LDL, VLDL, triglyceride and cholesterol were measured. Then the experiment group underwent the effect of an aerobic exercise program. After 12 weeks, all the measured variables before intervention the test were re-measured. Correlated t-test was used for comparing the two groups before and after intervention the test and independent t-test was used for comparing the two groups (P < 0.05).
The results showed that after 12 weeks of exercise, BMI, WHR, fat rate, weight and fat mass and triglyceride had significant reduction and HDL had significant increase. But no significant changes happened in LDL, VLDL, and cholesterol levels.
Reducing the weight by aerobic exercise in obese women and affected by PCOS can correct lipoprotein profile and improving health.
多囊卵巢综合征（PCOS）是最常见的内分泌疾病之一。PCOS表现为高雄激素血症、高血压以及胆固醇和脂蛋白谱异常。改变生活方式，如增加体育活动，是控制PCOS的首要方法。
24名经医学筛查确诊为多囊卵巢综合征（PCOS）的女性被分为两组：实验组（n = 12）和对照组（n = 12），平均年龄、体重、身高、体重指数（BMI）和腰臀比（WHR）分别为26.87 ± 4.43岁、75.71 ± 10.65千克、159.29 ± 6.44厘米、29.86 ± 3.22千克/平方米和91.75 ± 5.86。首先测量身体成分，如BMI、WHR、体脂百分比、体重和体脂量。在空腹血样中测量高密度脂蛋白（HDL）、低密度脂蛋白（LDL）、极低密度脂蛋白（VLDL）、甘油三酯和胆固醇水平。然后实验组进行有氧运动计划干预。12周后，重新测量干预前测试的所有变量。采用相关t检验比较两组干预前后的情况，采用独立t检验比较两组（P < 0.05）。
结果显示，运动12周后，BMI、WHR、脂肪率、体重、脂肪量和甘油三酯显著降低，HDL显著升高。但LDL、VLDL和胆固醇水平无显著变化。
肥胖且患有PCOS的女性通过有氧运动减轻体重可纠正脂蛋白谱并改善健康状况。
