Roberts C, Carlin W V
Department of Otolaryngology, North Staffordshire Royal Infirmary, Stoke-on-Trent, England.
Acta Otolaryngol. 1989 Nov-Dec;108(5-6):431-3. doi: 10.3109/00016488909125549.
To date there is no ideal method of painlessly achieving anaesthesia of the ear drum for myringotomy and grommet insertion. In this double blind, placebo controlled prospective study we have assessed a new topical anaesthetic agent (EMLA Cream) for use on keratinised squamous epithelium. A comparison has been made with the anaesthesia achieved by an injected agent. Twenty individuals were randomly allocated to receive placebo or EMLA cream. Their relative discomfort was measured on a visual analogue scale. Ten individuals received injected anaesthetic prior to myringotomy and grommet insertion and the discomfort of injection and of the procedure were similarly measured. We found EMLA cream to be an equally effective method of anaesthetising the ear drum as an injected agent. In addition there was minimal discomfort in the achievement of this anaesthesia. The discomfort of injecting the ear canal is shown to be similar to that of performing myringotomy and grommet insertion without anaesthesia.
迄今为止，尚无理想的方法能在鼓膜切开术和鼓膜置管术时无痛地实现鼓膜麻醉。在这项双盲、安慰剂对照的前瞻性研究中，我们评估了一种用于角化鳞状上皮的新型局部麻醉剂（EMLA乳膏）。并与注射剂麻醉效果进行了比较。20名受试者被随机分配接受安慰剂或EMLA乳膏。通过视觉模拟量表测量他们的相对不适感。10名受试者在鼓膜切开术和鼓膜置管术前接受注射麻醉剂，并同样测量注射和手术过程中的不适感。我们发现EMLA乳膏在麻醉鼓膜方面与注射剂同样有效。此外，实现这种麻醉时的不适感最小。结果表明，耳道注射的不适感与未麻醉情况下进行鼓膜切开术和鼓膜置管术的不适感相似。
