Keeley T, Al-Janabi H, Nicholls E, Foster N E, Jowett S, Coast J
MRC Midland Hub for Trials Methodology Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Health Economics Unit, School of Health and Population Sciences, Public Health Building, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Qual Life Res. 2015 Oct;24(10):2319-31. doi: 10.1007/s11136-015-0980-0. Epub 2015 Apr 18.
The ICECAP-A is a simple measure of capability well-being for use with the adult population. The descriptive system is made up of five key attributes: Stability, Attachment, Autonomy, Achievement and Enjoyment. Studies have begun to assess the psychometric properties of the measure, including the construct and content validity and feasibility for use. This is the first study to use longitudinal data to assess the responsiveness of the measure.
This responsiveness study was completed alongside a randomised controlled trial comparing three physiotherapy-led exercise interventions for older adults with knee pain attributable to osteoarthritis. Anchor-based methodologies were used to explore the relationship between change over time in ICECAP-A score (the target measure) and change over time in another measure (the anchor). Analyses were completed using the non-value-weighted and value-weighted ICECAP-A scores. The EQ-5D-3L was used as a comparator measure to contextualise change in the ICECAP-A. Effect sizes, standardised response means and t tests were used to quantify responsiveness.
Small changes in the ICECAP-A scores were seen in response to underlying changes in patients' health-related quality of life, anxiety and depression. Non-weighted scores were slightly more responsive than value-weighted scores. ICECAP-A change was of comparable size to change in the EQ-5D-3L reference measure.
This first analysis of the responsiveness using longitudinal data provides some positive evidence for the responsiveness of the ICECAP-A measure. There is a need for further research in those with low health and capability, and experiencing larger underlying changes in quality of life.
ICECAP - A是一种用于成年人群的简单的能力幸福感测量工具。该描述系统由五个关键属性组成：稳定性、依恋性、自主性、成就感和愉悦感。已有研究开始评估该测量工具的心理测量特性，包括结构效度、内容效度和使用的可行性。这是第一项使用纵向数据评估该测量工具反应性的研究。
这项反应性研究是在一项随机对照试验的同时完成的，该试验比较了三种由物理治疗师主导的运动干预措施，用于治疗因骨关节炎导致膝关节疼痛的老年人。基于锚定的方法被用来探索ICECAP - A评分（目标测量指标）随时间的变化与另一测量指标（锚定指标）随时间的变化之间的关系。分析使用了非价值加权和价值加权的ICECAP - A评分。EQ - 5D - 3L被用作比较测量指标，以说明ICECAP - A的变化情况。效应大小、标准化反应均值和t检验被用来量化反应性。
随着患者健康相关生活质量、焦虑和抑郁的潜在变化，ICECAP - A评分出现了微小变化。非加权评分的反应性略高于价值加权评分。ICECAP - A的变化幅度与EQ - 5D - 3L参考测量指标的变化幅度相当。
这项首次使用纵向数据对反应性进行的分析为ICECAP - A测量工具的反应性提供了一些积极证据。对于健康状况和能力较低、生活质量存在较大潜在变化的人群，仍需要进一步研究。
