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[从柳兰中分离委陵菜酸并通过微生物学试验评估其遗传毒性]

[Isolation of pomolic acid from Chamaenerion angustifolium and evaluation of its genotoxicity by microbiological tests].

作者信息

Frolova T S, Salnikova O I, Dudareva T A, Kukina T P, Synitsyna O I

出版信息

Bioorg Khim. 2014 Jan-Feb;40(1):92-8. doi: 10.1134/s1068162013060046.

DOI:10.1134/s1068162013060046
PMID:25898727
Abstract

Fireweed (Chamaenerion angustifolium) lipophilic constituents were investigated by GC-MS analysis. 28 aliphatic and 6 triterpenic acids were found out at first time. Pomolic acid genotoxicity and mutagenicity were analyzed by Ames test and SOS chromotest. Genotoxic and mutagenic properties of pomolic acid were not detected.

摘要

通过气相色谱-质谱联用(GC-MS)分析对柳叶菜(Chamaenerion angustifolium)的亲脂性成分进行了研究。首次发现了28种脂肪酸和6种三萜酸。通过艾姆斯试验(Ames test)和SOS显色试验分析了波摩酸的遗传毒性和致突变性。未检测到波摩酸的遗传毒性和致突变特性。

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Bioorg Khim. 2014 Jan-Feb;40(1):92-8. doi: 10.1134/s1068162013060046.
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