Als Lorraine C, Picouto Maria D, Hau Sau-Ming, Nadel Simon, Cooper Mehrengise, Pierce Christine M, Kramer Tami, Garralda M Elena
1Centre for Mental Health, Department of Medicine, Imperial College London, London, United Kingdom. 2Department of Child and Adolescent Psychiatry and Psychology, Sant Joan de Déu Hospital, Universitat de Barcelona, Barcelona, Spain. 3Department of Paediatric Intensive Care, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom. 4Department of Paediatric Intensive Care, Great Ormond Street Hospital, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.
Pediatr Crit Care Med. 2015 Jun;16(5):e141-9. doi: 10.1097/PCC.0000000000000424.
To assess mental and physical well-being in school-aged children following admission to pediatric intensive care and to examine risk factors for worse outcome.
A prospective cohort study.
Two PICUs.
A consecutive sample of 88 patients 5-16 years old (median age, 10.00 yr; interquartile range, 6.00-13.00 yr) admitted to PICU from 2007 to 2010 with septic illness, meningoencephalitis, or other critical illnesses were assessed a median of 5 months following discharge and outcomes compared with 100 healthy controls.
None.
Parents completed questionnaires documenting child mental and physical well-being, including the Strengths and Difficulties Questionnaires, Chalder Fatigue Scale, and Child Sleep Habits Questionnaire. Children over 8 years completed the Impact of Event Scale -8. The children admitted to PICU scored worse on all measures in comparison with the healthy controls, with 20% scoring at risk for psychiatric disorder, 34% with high levels of post-traumatic stress symptoms, 38% at risk for fatigue disorder, and 80% scoring at risk for sleep disturbance. In the PICU group, multivariable regression analyses identified septic illness as an independent predictor of post-traumatic stress symptoms and family status, past child health problems, and PICU length of stay as predictors of reduced general mental well-being.
Our findings indicate that a significant minority of school-aged children admitted to PICU are at risk for reduced mental and physical well-being in the short term. Symptoms of poor mental well-being were linked to both vulnerability factors and critical illness factors.
评估学龄儿童入住儿科重症监护病房后的身心健康状况,并研究不良预后的危险因素。
前瞻性队列研究。
两个儿科重症监护病房。
选取2007年至2010年因败血症、脑膜脑炎或其他危重症入住儿科重症监护病房的88例5至16岁患者(中位年龄10.00岁;四分位间距6.00 - 13.00岁),出院后中位5个月进行评估,并与100名健康对照者比较结局。
无。
父母完成记录儿童身心健康状况的问卷,包括长处与困难问卷、查尔德疲劳量表和儿童睡眠习惯问卷。8岁以上儿童完成事件影响量表 - 8。与健康对照者相比,入住儿科重症监护病房的儿童在所有测量指标上得分更低,20%有精神障碍风险,34%有高水平创伤后应激症状,38%有疲劳障碍风险,80%有睡眠障碍风险。在儿科重症监护病房组,多变量回归分析确定败血症是创伤后应激症状的独立预测因素,家庭状况、既往儿童健康问题和儿科重症监护病房住院时间是总体心理健康状况下降的预测因素。
我们的研究结果表明,入住儿科重症监护病房的学龄儿童中有相当一部分在短期内存在身心健康下降的风险。心理健康不佳的症状与脆弱因素和危重症因素均有关联。