Saeed Intisar Kamil, Ali Yahia Hassan, AbdulRahman Magdi Badawi, Mohammed Zakia Abas, Osman Halima Mohammed, Taha Khalid Mohammed, Musa Mohammed Zain, Khalafalla AbdelMelik Ibrahim
Central Veterinary Research Laboratory, P.O.Box 8067, Al Amarat, Khartoum, Sudan,
Trop Anim Health Prod. 2015 Jun;47(5):995-8. doi: 10.1007/s11250-015-0798-3. Epub 2015 Apr 24.
This study was intended to determine the role played by peste des petits ruminants (PPR) in causing respiratory infections in camels and its association with other respiratory viruses. A total of 474 lung specimens showing pneumonia were collected from clinically healthy camels in slaughterhouses at five different areas in Sudan. Using immunocapture ELISA (IcELISA), 214 specimens (45.1 %) were found to be positive for PPR antigen. The highest prevalence was found in central Sudan (59.9 %) then northern Sudan (56.6 %) and eastern Sudan (26.6 %). Parainfluenza virus 3 (PIV 3), respiratory syncytial virus (RSV), bovine herpes virus-1 (BHV-1), bovine viral diarrhea (BVD), and adenovirus were detected in 4.4, 2.9, 2.0, 9.0, and 1.3 % of the specimens, respectively. PPR antigen was found in about 50 % of specimens that showed positive result for other viral antigens. Twenty-five of 28 BVD, 15 of 16 PIV3, 8 of 12 RSV, 4 of 4 adenovirus, and 4 of 5 BHV-1 were found in association with other respiratory antigens. Results revealed the existence of PPRV infection in dromedary camels in Sudan and present evidence for mixed virus infection, suggesting that respiratory infections in camels might be exacerbated by PPRV.
本研究旨在确定小反刍兽疫（PPR）在骆驼呼吸道感染中所起的作用及其与其他呼吸道病毒的关联。从苏丹五个不同地区屠宰场的临床健康骆驼身上共采集了474份显示肺炎的肺标本。使用免疫捕获ELISA（IcELISA）检测发现，214份标本（45.1%）的PPR抗原呈阳性。在苏丹中部患病率最高（59.9%），其次是苏丹北部（56.6%）和苏丹东部（26.6%）。分别在4.4%、2.9%、2.0%、9.0%和1.3%的标本中检测到副流感病毒3型（PIV 3）、呼吸道合胞病毒（RSV）、牛疱疹病毒1型（BHV - 1）、牛病毒性腹泻（BVD）和腺病毒。在其他病毒抗原检测呈阳性的标本中，约50%发现了PPR抗原。在28份BVD标本中有25份、16份PIV3标本中有15份、12份RSV标本中有8份、4份腺病毒标本中有4份以及5份BHV - 1标本中有4份与其他呼吸道抗原同时存在。结果显示苏丹单峰骆驼中存在PPRV感染，并为混合病毒感染提供了证据，表明PPRV可能会加重骆驼的呼吸道感染。
