Dominici Francesca, Wang Yun, Correia Andrew W, Ezzati Majid, Pope C Arden, Dockery Douglas W
From the aDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA; bNMR Group, Inc., Somerville, MA; cMRC-PHE Centre for Environment and Health and Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom; dDepartment of Economics, Brigham Young University, Provo, UT; and eDepartment of Environmental Health, fDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Epidemiology. 2015 Jul;26(4):556-64. doi: 10.1097/EDE.0000000000000297.
In a previous study, we provided evidence that a decline in fine particulate matter (PM2.5) air pollution during the period between 2000 and 2007 was associated with increased life expectancy in 545 counties in the United States. In this article, we investigated which chemical constituents of PM2.5 were the main drivers of the observed association.
We estimated associations between temporal changes in seven major components of PM2.5 (ammonium, sulfate, nitrate, elemental carbon matter, organic carbon matter, sodium, and silicon) and temporal changes in life expectancy in 95 counties between 2002 and 2007. We included US counties that had adequate chemical components of PM2.5 mass data across all seasons. We fitted single pollutant and multiple pollutant linear models, controlling for available socioeconomic, demographic, and smoking variables and stratifying by urban and nonurban counties.
In multiple pollutant models, we found that: (1) a reduction in sulfate was associated with an increase in life expectancy; and (2) reductions in ammonium and sodium ion were associated with increases in life expectancy in nonurban counties only.
Our findings suggest that recent reductions in long-term exposure to sulfate, ammonium, and sodium ion between 2002 and 2007 are associated with improved public health.
在之前的一项研究中,我们提供了证据表明,2000年至2007年期间细颗粒物(PM2.5)空气污染的下降与美国545个县预期寿命的增加有关。在本文中,我们调查了PM2.5的哪些化学成分是观察到的这种关联的主要驱动因素。
我们估计了2002年至2007年期间95个县PM2.5的七种主要成分(铵、硫酸盐、硝酸盐、元素碳物质、有机碳物质、钠和硅)的时间变化与预期寿命的时间变化之间的关联。我们纳入了在所有季节都有足够PM2.5质量数据化学成分的美国各县。我们拟合了单污染物和多污染物线性模型,控制了可用的社会经济、人口和吸烟变量,并按城市和非城市县进行分层。
在多污染物模型中,我们发现:(1)硫酸盐的减少与预期寿命的增加有关;(2)铵和钠离子的减少仅与非城市县预期寿命的增加有关。
我们的研究结果表明,2002年至2007年期间长期接触硫酸盐、铵和钠离子的近期减少与公众健康的改善有关。