Torres-Sánchez Irene, Rodríguez-Alzueta Elisabeth, Cabrera-Martos Irene, López-Torres Isabel, Moreno-Ramírez Maria Paz, Valenza Marie Carmen
Department of Physical Therapy, Health Sciences Faculty, University of Granada, Granada, Spain.
J Bras Pneumol. 2015 Mar-Apr;41(2):182-90. doi: 10.1590/S1806-37132015000004424. Epub 2015 Apr 18.
The objectives of this study were to characterize and clarify the relationships between the various cognitive domains affected in COPD patients and the disease itself, as well as to determine the prevalence of impairment in the various cognitive domains in such patients. To that end, we performed a systematic review using the following databases: PubMed, Scopus, and ScienceDirect. We included articles that provided information on cognitive impairment in COPD patients. The review of the findings of the articles showed a significant relationship between COPD and cognitive impairment. The most widely studied cognitive domains are memory and attention. Verbal memory and learning constitute the second most commonly impaired cognitive domain in patients with COPD. The prevalence of impairment in visuospatial memory and intermediate visual memory is 26.9% and 19.2%, respectively. We found that cognitive impairment is associated with the profile of COPD severity and its comorbidities. The articles reviewed demonstrated that there is considerable impairment of the cognitive domains memory and attention in patients with COPD. Future studies should address impairments in different cognitive domains according to the disease stage in patients with COPD.
本研究的目的是描述和阐明慢性阻塞性肺疾病（COPD）患者受影响的各个认知领域与疾病本身之间的关系，并确定此类患者各个认知领域的损伤患病率。为此，我们使用以下数据库进行了系统综述：PubMed、Scopus和ScienceDirect。我们纳入了提供COPD患者认知障碍信息的文章。对文章研究结果的综述表明，COPD与认知障碍之间存在显著关系。研究最广泛的认知领域是记忆和注意力。言语记忆和学习是COPD患者第二常见的受损认知领域。视觉空间记忆和中度视觉记忆的损伤患病率分别为26.9%和19.2%。我们发现认知障碍与COPD严重程度及其合并症情况有关。所综述的文章表明，COPD患者的认知领域记忆和注意力存在相当程度的损伤。未来的研究应根据COPD患者的疾病阶段解决不同认知领域的损伤问题。
