[Depressive state complicated with chronic renal failure treated by continuous ambulatory peritoneal dialysis].

Thirty two cases of chronic renal failure with Continuous Ambulatory Peritoneal Dialysis (CAPD) hospitalized from November, 1984 to July, 1986 were investigated by interview, Hamilton Depression Scale (HAMD) and Symptom Check List (SCL-90). Results revealed that the occurrence of depression among dialyzed patients was 56.3%, i.e. 18 patients with high total score of HAMD belonged to organic affective syndrome defined by DSM-III. Causes of developing depression during CAPD were evaluated and analyzed. Authors consider that depression should be viewed as interaction of genetic, psychosocial and neurobiological variables.