Kahleova Hana, Pelikanova Terezie
a Institute for Clinical and Experimental Medicine , Prague , CZECH REPUBLIC.
J Am Coll Nutr. 2015;34(5):448-58. doi: 10.1080/07315724.2014.976890. Epub 2015 Apr 27.
Observational studies show that prevalence of type 2 diabetes is 1.6 to 2 times lower in vegetarians than in the general population, even after adjustment for differences in body mass index (BMI). Clinical interventional trials demonstrated that vegetarian diets lead to a greater weight loss and greater reduction in fasting plasma glucose, HbA1c, blood lipids, and hypoglycemic medication than a conventional hypocaloric diet in subjects with type 2 diabetes. We found a greater reduction in visceral fat and greater improvements in insulin resistance and oxidative stress markers with a vegetarian compared to a conventional hypocaloric diabetic diet. Vegetarian diets are sustainable in the long term and may elicit desirable improvements not only in physical health but also in mental health. The American Dietetic Association states that well-planned vegetarian diets are healthy and nutritionally adequate and they may be beneficial in prevention and treatment of some illnesses. Larger clinical trials are needed to confirm the effectiveness and promote the inclusion of vegetarian diets in dietary guidelines for prevention and treatment of type 2 diabetes.
观察性研究表明,即使在对体重指数(BMI)差异进行调整之后,素食者中2型糖尿病的患病率也比普通人群低1.6至2倍。临床干预试验表明,与传统的低热量饮食相比,素食饮食能使2型糖尿病患者体重减轻更多,空腹血糖、糖化血红蛋白、血脂降低更多,降糖药物使用减少更多。我们发现,与传统的低热量糖尿病饮食相比,素食饮食能使内脏脂肪减少更多,胰岛素抵抗和氧化应激标志物改善更明显。素食饮食从长期来看是可持续的,不仅可能给身体健康带来理想的改善,还可能对心理健康有益。美国营养与饮食学会指出,精心规划的素食饮食是健康且营养充足的,可能有助于预防和治疗某些疾病。需要开展更大规模的临床试验来证实其有效性,并推动将素食饮食纳入2型糖尿病防治的饮食指南中。