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在中国猪场分离出的奇异变形杆菌菌株中发现的两种新型沙门氏菌基因组岛1变体。

Two novel Salmonella genomic island 1 variants in Proteus mirabilis isolates from swine farms in China.

作者信息

Lei Chang-Wei, Zhang An-Yun, Liu Bi-Hui, Wang Hong-Ning, Yang Li-Qin, Guan Zhong-Bin, Xu Chang-Wen, Zhang Dong-Dong, Yang Yong-Qiang

机构信息

Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, People's Republic of China College of Life Science, Sichuan University, Chengdu, People's Republic of China.

Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, People's Republic of China 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, People's Republic of China College of Life Science, Sichuan University, Chengdu, People's Republic of China

出版信息

Antimicrob Agents Chemother. 2015 Jul;59(7):4336-8. doi: 10.1128/AAC.00120-15. Epub 2015 Apr 27.

Abstract

Four different Salmonella genomic island 1 (SGI1) variants, including two novel variants, were characterized in one Salmonella enterica serovar Rissen sequence type ST1917 isolate and three Proteus mirabilis isolates from swine farms in China. One novel variant was derived from SGI1-B with the backbone gene S021 disrupted by a 12.72-kb IS26 composite transposon containing the dfrA17-aadA5 cassettes and macrolide inactivation gene cluster mphA-mrx-mphR. The other one was an integron-free SGI1 and contained a 183-bp truncated S025 next to IS6100 and S044.

摘要

在中国的一个猪养殖场的一株肠炎沙门氏菌血清型里森序列型ST1917分离株和三株奇异变形杆菌分离株中,鉴定出了四种不同的沙门氏菌基因组岛1(SGI1)变体,包括两种新变体。一种新变体源自SGI1-B,其骨干基因S021被一个12.72 kb的IS26复合转座子破坏,该转座子包含dfrA17-aadA5盒式结构和大环内酯失活基因簇mphA-mrx-mphR。另一种是无整合子的SGI1,在IS6100和S044旁边含有一个183 bp的截短S025。

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本文引用的文献

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The complete sequence of Salmonella genomic island SGI2.沙门氏菌基因组岛SGI2的完整序列。
J Antimicrob Chemother. 2015 Feb;70(2):617-9. doi: 10.1093/jac/dku407. Epub 2014 Oct 14.
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The complete sequence of Salmonella genomic island SGI1-K.鼠伤寒沙门氏菌基因组岛SGI1-K的完整序列。
J Antimicrob Chemother. 2015 Jan;70(1):305-6. doi: 10.1093/jac/dku331. Epub 2014 Sep 4.

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