PGI2 是一种新型的与 SGI1 相关的多药耐药基因组岛，存在于奇异变形杆菌中。
PGI2 Is a Novel SGI1-Relative Multidrug-Resistant Genomic Island Characterized in Proteus mirabilis.
机构信息
Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, People's Republic of China.
Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China.
出版信息
Antimicrob Agents Chemother. 2018 Apr 26;62(5). doi: 10.1128/AAC.00019-18. Print 2018 May.
Abstract
A novel 61,578-bp genomic island named genomic island 2 (PGI2) was characterized in of swine origin in China. The 23.85-kb backbone of PGI2 is related to those of genomic island 1 and genomic island 1. The multidrug resistance (MDR) region of PGI2 is a complex class 1 integron containing 14 different resistance genes. PGI2 was conjugally mobilized in to in the presence of a conjugative IncC helper plasmid.
摘要
在中国起源的猪源 中，鉴定出一个新型的 61578 碱基对的基因组岛，命名为基因组岛 2（PGI2）。PGI2 的 23.85kb 骨架与基因组岛 1 和基因组岛 1 的相关。PGI2 的多药耐药（MDR）区域是一个复杂的类 1 整合子，包含 14 个不同的耐药基因。在携带可接合 IncC 辅助质粒的情况下，PGI2 在 中被接合转移到 中。
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