三种多功能消毒溶液对硅水凝胶隐形眼镜的性能研究

Performance of three multipurpose disinfecting solutions with a silicone hydrogel contact lens.

作者信息

García-Porta Nery, Rico-del-Viejo Laura, Ferreira-Neves Helena, Peixoto-de-Matos Sofia C, Queirós Antonio, González-Méijome José M

机构信息

Clinical & Experimental Optometry Research Lab, Center of Physics (Optometry), University of Minho, 4710-057 Braga, Portugal ; Ocular Surface and Contact Lenses Research Group, University of Santiago de Compostela, 15782 A Coruña, Spain.

Clinical & Experimental Optometry Research Lab, Center of Physics (Optometry), University of Minho, 4710-057 Braga, Portugal.

出版信息

Biomed Res Int. 2015;2015:216932. doi: 10.1155/2015/216932. Epub 2015 Mar 31.

DOI:10.1155/2015/216932

PMID:25918703

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4396003/

Abstract

PURPOSE

To evaluate the clinical performance of a silicone hydrogel (Si-Hy) soft contact lens (CL) in combination with three different multipurpose disinfecting solutions (MPDSs).

METHODS

This was a prospective, randomized, single-masked, crossover, and comparative study in which 31 habitual soft CL wearers were randomly assigned to one of the three MPDSs (Synergi, COMPLETE RevitaLens, and OPTI-FREE PureMoist) for 1 month with a 1-week wash-out period between each exposure. All subjects were successfully refitted with a Si-Hy CL (Biofinity). Subjects were then scheduled for follow-up visits after 1 month of lens wear, being evaluated at 2 and 8 hours after lens insertion. Visual Analogue Scales (VAS) were used to gauge comfort rating.

RESULTS

The tarsal conjunctiva showed a significantly different degree of lid redness between the MPDSs at the 2-hour visit (P < 0.05, Kruskal-Wallis test), being lower for COMPLETE RevitaLens compared to the other two MPDSs (Mann-Whitney U test). Furthermore, a significantly different degree of lid roughness at the 8-hour visit was seen (P < 0.05, Kruskal-Wallis test), being higher for Synergi (Mann-Whitney U test). The subjective comfort was similar with the three MPDSs.

CONCLUSION

Tarsal conjunctival response should be also considered in the context of the clinical performance of MPDs at the ocular surface.

摘要

目的

评估硅水凝胶（Si-Hy）软性接触镜（CL）与三种不同的多功能消毒护理液（MPDS）联合使用时的临床性能。

方法

这是一项前瞻性、随机、单盲、交叉对照研究，31名习惯性软性CL佩戴者被随机分配至三种MPDS（Synergi、COMPLETE RevitaLens和OPTI-FREE PureMoist）中的一种，使用1个月，每次使用之间有1周的洗脱期。所有受试者均成功重新佩戴Si-Hy CL（Biofinity）。佩戴镜片1个月后安排受试者进行随访，在镜片插入后2小时和8小时进行评估。使用视觉模拟量表（VAS）来评估舒适度。

结果

在2小时随访时，睑结膜显示不同MPDS之间睑部发红程度有显著差异（P<0.05，Kruskal-Wallis检验），与其他两种MPDS相比，COMPLETE RevitaLens的睑部发红程度较低（Mann-Whitney U检验）。此外，在8小时随访时观察到睑部粗糙度有显著差异（P<0.05，Kruskal-Wallis检验），Synergi的睑部粗糙度较高（Mann-Whitney U检验）。三种MPDS的主观舒适度相似。