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乳糜泻的心理发病机制:文献综述。

Psychological morbidity of celiac disease: A review of the literature.

机构信息

University of Salerno, Department of Medicine and Surgery, Salerno, Italy.

Department of Gastroenterology, University Hospital Llandough, Cardiff, Wales, UK.

出版信息

United European Gastroenterol J. 2015 Apr;3(2):136-45. doi: 10.1177/2050640614560786.

DOI:10.1177/2050640614560786
PMID:25922673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4406898/
Abstract

BACKGROUND

Celiac disease has been linked to decreased quality of life and certain mood disorders. The effect of the gluten free diet on these psychological aspects of the disease is still unclear.

OBJECTIVES

The objective of this article is to review the literature on psychological morbidity of celiac disease.

METHODS

We performed a PubMed search for the time period from 1900 until June 1, 2014, to identify papers on psychological aspects of celiac disease looking specifically at quality of life, anxiety, depression and fatigue.

RESULTS

Anxiety, depression and fatigue are common complaints in patients with untreated celiac disease and contribute to lower quality of life. While aspects of these conditions may improve within a few months after starting a gluten-free diet, some patients continue to suffer from significant psychological morbidity. Psychological symptoms may affect the quality of life and the dietary adherence.

CONCLUSION

Health care professionals need to be aware of the ongoing psychological burden of celiac disease in order to support patients with this disease.

摘要

背景

乳糜泻与生活质量下降和某些情绪障碍有关。无麸质饮食对这种疾病的心理方面的影响尚不清楚。

目的

本文旨在回顾乳糜泻心理发病机制的文献。

方法

我们对从 1900 年到 2014 年 6 月 1 日的文献进行了 PubMed 搜索,以确定研究乳糜泻心理方面的论文,特别是关注生活质量、焦虑、抑郁和疲劳。

结果

焦虑、抑郁和疲劳是未经治疗的乳糜泻患者常见的主诉,导致生活质量下降。尽管在开始无麸质饮食后的几个月内,这些疾病的某些方面可能会有所改善,但一些患者仍继续遭受严重的心理困扰。心理症状可能会影响生活质量和饮食的坚持。

结论

医疗保健专业人员需要意识到乳糜泻的持续心理负担,以便为患者提供支持。

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本文引用的文献

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Gastroenterology. 2014 Sep;147(3):610-617.e1. doi: 10.1053/j.gastro.2014.05.003. Epub 2014 May 13.
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