Hill Jonathan C, Thomas Elaine, Hill Susan, Foster Nadine E, van der Windt Danielle A
Institute of Primary Care and Health Sciences, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom.
PLoS One. 2015 Apr 30;10(4):e0124557. doi: 10.1371/journal.pone.0124557. eCollection 2015.
To develop and validate a patient report outcome measure (PROM) for clinical practice that can monitor health status of patients with a range of musculoskeletal (MSK) disorders.
Constructs for inclusion in the MSK-PROM were identified from a consensus process involving patients with musculoskeletal conditions, clinicians, purchasers of healthcare services, and primary care researchers. Psychometric properties of the brief tool, including face and construct validity, repeatability and responsiveness were assessed in a sample of patients with musculoskeletal pain consulting physiotherapy services in the United Kingdom (n=425).
The consensus process identified 10 prioritised domains for monitoring musculoskeletal health status: pain intensity, quality of life, physical capacity, interference with social/leisure activities, emotional well-being, severity of most difficult thing, activities and roles, understanding independence, and overall impact. As the EuroQol (EQ-5D-5L) is a widely adopted PROMs tool and covers the first four domains listed, to reduce patient burden to a minimum the MSK-PROM was designed to capture the remaining six prioritised domains which are not measured by the EQ-5D-5L. The tool demonstrated excellent reliability, construct validity, responsiveness and acceptability to patients and clinicians for use in clinical practice.
We have validated a brief patient reported outcome measure (MSK-PROM) for use in clinical practice to measure musculoskeletal health status and monitor outcomes over time using domains that are meaningful to patients and sensitive to change. Further work will establish whether the MSK-PROM is useful in other musculoskeletal healthcare settings.
开发并验证一种用于临床实践的患者报告结局测量工具（PROM），该工具可监测一系列肌肉骨骼（MSK）疾病患者的健康状况。
通过一个由肌肉骨骼疾病患者、临床医生、医疗服务购买者和初级保健研究人员参与的共识过程，确定纳入MSK-PROM的指标。在英国接受物理治疗服务的肌肉骨骼疼痛患者样本（n = 425）中，评估了该简短工具的心理测量特性，包括表面效度和结构效度、重复性和反应性。
共识过程确定了10个监测肌肉骨骼健康状况的优先领域：疼痛强度、生活质量、身体能力、对社交/休闲活动的干扰、情绪健康、最困难事情的严重程度、活动和角色、对独立性的理解以及总体影响。由于欧洲生活质量量表（EQ-5D-5L）是一种广泛采用的PROMs工具，涵盖了列出的前四个领域，为了将患者负担降至最低，MSK-PROM被设计用于捕捉EQ-5D-5L未测量的其余六个优先领域。该工具在临床实践中对患者和临床医生显示出优异的可靠性、结构效度、反应性和可接受性。
我们已经验证了一种简短的患者报告结局测量工具（MSK-PROM），可用于临床实践，以测量肌肉骨骼健康状况，并使用对患者有意义且对变化敏感的领域随时间监测结局。进一步的工作将确定MSK-PROM在其他肌肉骨骼医疗环境中是否有用。
