Dotto Bruno Reis, Carvalho Evelise Leis, Silva Alexandre Freitas, Duarte Silva Luiz Fernando, Pinto Paulo Marcos, Ortiz Mauro Freitas, Wallau Gabriel Luz
Campus São Gabriel, Universidade Federal do Pampa, São Gabriel.
Pós Graduação em Ciências Biológicas, Universidade Federal do Pampa, São Gabriel and.
Bioinformatics. 2015 Sep 1;31(17):2915-7. doi: 10.1093/bioinformatics/btv281. Epub 2015 May 4.
Horizontal transfer of transposable (HTT) elements among eukaryotes was discovered in the mid-1980s. As then, >300 new cases have been described. New findings about HTT are revealing the evolutionary impact of this phenomenon on host genomes. In order to provide an up to date, interactive and expandable database for such events, we developed the HTT-DB database.
HTT-DB allows easy access to most of HTT cases reported along with rich information about each case. Moreover, it allows the user to generate tables and graphs based on searches using Transposable elements and/or host species classification and export them in several formats.
This database is freely available on the web at http://lpa.saogabriel.unipampa.edu.br:8080/httdatabase. HTT-DB was developed based on Java and MySQL with all major browsers supported. Tools and software packages used are free for personal or non-profit projects.
转座元件在真核生物间的水平转移（HTT）于20世纪80年代中期被发现。自那时起，已描述了300多个新案例。关于HTT的新发现正在揭示这一现象对宿主基因组的进化影响。为了为这类事件提供一个最新的、交互式且可扩展的数据库，我们开发了HTT-DB数据库。
HTT-DB允许轻松访问大多数已报道的HTT案例，并提供有关每个案例的丰富信息。此外，它允许用户根据使用转座元件和/或宿主物种分类进行的搜索生成表格和图表，并以多种格式导出。
