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应对乳腺癌及复发:一项为期10年的观察性研究中应对方式的稳定性及长期结果

Coping with breast cancer and relapse: Stability of coping and long-term outcomes in an observational study over 10 years.

作者信息

Geyer Siegfried, Koch-Giesselmann Heike, Noeres Dorothee

机构信息

Medical Sociology Unit, Hannover Medical School, Germany.

Medical Sociology Unit, Hannover Medical School, Germany; Clinics of the Hannover Region, Hospital Oststadt, Hannover, Germany.

出版信息

Soc Sci Med. 2015 Jun;135:92-8. doi: 10.1016/j.socscimed.2015.04.027. Epub 2015 Apr 26.

Abstract

Many studies dealing with relationships between coping and breast cancer were based on a single measurement of coping behaviour. Assessments were taking place soon after surgery of primary breast cancer, and effects on long-term outcomes were considered. In our study it was examined whether coping behaviours are stable over time and whether they were associated with breast cancer recurrence. The analyses were based on a long-term study with initially 254 patients with three interviews and an outcome assessment within a total study period of 10 years. Data were collected by means of qualitative interviews and standardized questionnaires. Ways of coping in terms of helplessness, denial, mastery, and hope/optimism were classified by interviewer-based ratings within the framework of a standardized rating procedure. The reliability of rating standards was assured by continuous training and by estimating inter-rater agreements. Outcome measures were drawn from registries and patients' files. Coping behaviours over three interviews within six years after surgery turned out to be highly variable, and the respective correlations were low. For none of the four ways of coping associations with recurrence emerged. Coping in response to breast cancer was not stable over time, so we may conclude that the results of one measurement assessed early in the disease course should not be considered as constant over longer time periods. Coping behaviours were unrelated with recurrence, a finding that might be relieving from a patient perspective.

摘要

许多关于应对方式与乳腺癌之间关系的研究都是基于对应对行为的单一测量。评估在原发性乳腺癌手术后不久进行,并考虑其对长期结果的影响。在我们的研究中,我们考察了应对行为是否随时间稳定,以及它们是否与乳腺癌复发相关。分析基于一项长期研究,最初有254名患者,在总共10年的研究期内进行了三次访谈和一次结果评估。数据通过定性访谈和标准化问卷收集。在标准化评分程序的框架内,由访谈者根据评分对无助、否认、掌控和希望/乐观等应对方式进行分类。通过持续培训和评估评分者间的一致性来确保评分标准的可靠性。结果测量来自登记处和患者档案。手术后六年内三次访谈中的应对行为变化很大,各自的相关性很低。四种应对方式中没有一种与复发相关。应对乳腺癌的方式随时间不稳定,因此我们可以得出结论,在疾病过程早期进行的一次测量结果不应被视为在较长时间段内是恒定的。应对行为与复发无关,从患者角度来看,这一发现可能会让人感到宽慰。

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