Jennings Lance C, Priest Patricia C, Psutka Rebecca A, Duncan Alasdair R, Anderson Trevor, Mahagamasekera Patalee, Strathdee Andrew, Baker Michael G
Virology Section, Canterbury Health Laboratories, and Pathology Department, University of Otago, Christchurch 8011, New Zealand.
Department of Preventive and Social Medicine, University of Otago, Dunedin 9054, New Zealand.
J Clin Virol. 2015 Jun;67:8-13. doi: 10.1016/j.jcv.2015.03.011. Epub 2015 Mar 14.
There is very little known about the prevalence and distribution of respiratory viruses, other than influenza, in international air travellers and whether symptom screening would aid in the prediction of which travellers are more likely to be infected with specific respiratory viruses.
In this study, we investigate whether, the use of a respiratory symptom screening tool at the border would aid in predicting which travellers are more likely to be infected with specific respiratory viruses.
Data were collected from travellers arriving at Christchurch International Airport, New Zealand, during the winter 2008, via a symptom questionnaire, temperature testing, and respiratory sampling.
Respiratory viruses were detected in 342 (26.0%) of 1313 samples obtained from 2714 symptomatic travellers. The most frequently identified viruses were rhinoviruses (128), enteroviruses (77) and influenza B (48). The most frequently reported symptoms were stuffy or runny nose (60%), cough (47%), sore throat (27%) and sneezing (24%). Influenza B infections were associated with the highest number of symptoms (mean of 3.4) followed by rhinoviruses (mean of 2.2) and enteroviruses (mean of 1.9). The positive predictive value (PPV) of any symptom for any respiratory virus infection was low at 26%.
The high prevalence of respiratory virus infections caused by viruses other than influenza in this study, many with overlapping symptotology to influenza, has important implications for any screening strategies for the prediction of influenza in airline travellers.
除流感外，关于国际航空旅客中呼吸道病毒的流行率和分布情况，以及症状筛查是否有助于预测哪些旅客更有可能感染特定呼吸道病毒，我们所知甚少。
在本研究中，我们调查在边境使用呼吸道症状筛查工具是否有助于预测哪些旅客更有可能感染特定呼吸道病毒。
通过症状问卷、体温检测和呼吸道采样，收集了2008年冬季抵达新西兰克赖斯特彻奇国际机场的旅客的数据。
从2714名有症状的旅客中采集的1313份样本中，有342份（26.0%）检测出呼吸道病毒。最常检测到的病毒是鼻病毒（128例）、肠道病毒（77例）和乙型流感病毒（48例）。最常报告的症状是鼻塞或流涕（60%）、咳嗽（47%）、喉咙痛（27%）和打喷嚏（24%）。乙型流感病毒感染的症状数量最多（平均3.4个），其次是鼻病毒（平均2.2个）和肠道病毒（平均1.9个）。任何症状对任何呼吸道病毒感染的阳性预测值（PPV）较低，为26%。
本研究中除流感外的病毒引起的呼吸道病毒感染患病率较高，许多症状与流感重叠，这对预测航空旅客流感的任何筛查策略都具有重要意义。
