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荷兰分娩开始时由助产士主导护理与由产科医生主导护理的产妇严重不良结局:一项全国性队列研究

Severe Adverse Maternal Outcomes among Women in Midwife-Led versus Obstetrician-Led Care at the Onset of Labour in the Netherlands: A Nationwide Cohort Study.

作者信息

de Jonge Ank, Mesman Jeanette A J M, Manniën Judith, Zwart Joost J, Buitendijk Simone E, van Roosmalen Jos, van Dillen Jeroen

机构信息

Department of Midwifery Science, AVAG and the EMGO Institute of Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.

Leiden University Medical Center, Department of Obstetrics, Leiden, the Netherlands.

出版信息

PLoS One. 2015 May 11;10(5):e0126266. doi: 10.1371/journal.pone.0126266. eCollection 2015.

Abstract

OBJECTIVE

To test the hypothesis that it is possible to select a group of low risk women who can start labour in midwife-led care without having increased rates of severe adverse maternal outcomes compared to women who start labour in secondary care.

DESIGN AND METHODS

We conducted a nationwide cohort study in the Netherlands, using data from 223 739 women with a singleton pregnancy between 37 and 42 weeks gestation without a previous caesarean section, with spontaneous onset of labour and a child in cephalic presentation. Information on all cases of severe acute maternal morbidity collected by the national study into ethnic determinants of maternal morbidity in the Netherlands (LEMMoN study), 1 August 2004 to 1 August 2006, was merged with data from the Netherlands Perinatal Registry of all births occurring during the same period. Our primary outcome was severe acute maternal morbidity (SAMM, i.e. admission to an intensive care unit, uterine rupture, eclampsia or severe HELLP, major obstetric haemorrhage, and other serious events). Secondary outcomes were postpartum haemorrhage and manual removal of placenta.

RESULTS

Nulliparous and parous women who started labour in midwife-led care had lower rates of SAMM, postpartum haemorrhage and manual removal of placenta compared to women who started labour in secondary care. For SAMM the adjusted odds ratio's and 95% confidence intervals were for nulliparous women: 0.57 (0.45 to 0.71) and for parous women 0.47 (0.36 to 0.62).

CONCLUSIONS

Our results suggest that it is possible to identify a group of women at low risk of obstetric complications who may benefit from midwife-led care. Women can be reassured that we found no evidence that midwife-led care at the onset of labour is unsafe for women in a maternity care system with a well developed risk selection and referral system.

摘要

目的

检验以下假设,即与在二级医疗机构开始分娩的女性相比,有可能选出一组低风险女性,她们在助产士主导的护理下开始分娩,且严重不良孕产妇结局发生率不增加。

设计与方法

我们在荷兰进行了一项全国性队列研究,使用了223739名单胎妊娠女性的数据,这些女性妊娠37至42周,未曾行剖宫产,自然发动分娩且胎儿为头先露。将荷兰全国孕产妇发病率种族决定因素研究(LEMMoN研究)于2004年8月1日至2006年8月1日收集的所有严重急性孕产妇发病病例信息,与同期荷兰围产期登记处所有出生数据合并。我们的主要结局是严重急性孕产妇发病(SAMM,即入住重症监护病房、子宫破裂、子痫或重度HELLP、严重产科出血及其他严重事件)。次要结局是产后出血和徒手剥离胎盘。

结果

与在二级医疗机构开始分娩的女性相比,在助产士主导的护理下开始分娩的初产妇和经产妇的SAMM、产后出血和徒手剥离胎盘发生率较低。对于SAMM,初产妇的校正比值比及95%置信区间为0.57(0.45至0.71),经产妇为0.47(0.36至0.62)。

结论

我们的数据表明,有可能识别出一组产科并发症低风险女性,她们可能从助产士主导的护理中获益。可以让女性放心,我们没有发现证据表明,在一个具备完善风险筛选和转诊系统的孕产妇护理体系中,分娩开始时由助产士主导的护理对女性不安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2719/4427485/6ad716ec0a54/pone.0126266.g001.jpg

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