来自多裂凤尾蕨的一种不寻常的二氢苯并呋喃异香豆素和对映贝壳杉烷二萜类化合物。
An unusual dihydrobenzofuroisocoumarin and ent-kaurane diterpenoids from Pteris multifida.
作者信息
Ni Gang, Fu Nai-Jie, Zhang Di, Yang Han-Ze, Chen Xiao-Guang, Yu De-Quan
机构信息
a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Chinese Academy of Medical Sciences and Peking Union Medical College, Institute of Materia Medica , Beijing 100050 , China.
出版信息
J Asian Nat Prod Res. 2015 May;17(5):423-9. doi: 10.1080/10286020.2015.1040777. Epub 2015 May 13.
An unusual 5-C-methylated-dihydrobenzofuroisocoumarin, named multifidarin A (1), and two new ent-kaurane diterpenoids, named multikauranes A (2) and B (3), together with three known ent-kaurane diterpenoids, were isolated from the whole plants of Pteris multifida. The structures of 1-3 were elucidated by spectroscopic methods. The cytotoxic activities of all new compounds were evaluated against five human tumor cell lines. A possible biosynthetic process for the formation of 1 is proposed.
从凤尾草全草中分离得到一个罕见的5-C-甲基化二氢苯并呋喃异香豆素，命名为多裂素A（1），以及两个新的对映-贝壳杉烷二萜，命名为多裂贝壳杉烷A（2）和B（3），还有三个已知的对映-贝壳杉烷二萜。通过光谱方法阐明了1-3的结构。评估了所有新化合物对五种人类肿瘤细胞系的细胞毒活性。提出了1形成的可能生物合成过程。
Zotero 插件