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黄精属植物的化学成分及其在医学治疗中的作用。

Chemical constituents of the genus Polygonatum and their role in medicinal treatment.

作者信息

Zhao Xueying, Li Ji

出版信息

Nat Prod Commun. 2015 Apr;10(4):683-8.

PMID:25973509
Abstract

Polygonatum is a famous traditional Chinese medicine that is widely used in China, Korea and Japan. In the last decade, constituents of the genus have been reported including steroidal saponins, flavones, alkaloids, lignins, amino acids and carbohydrates, some of which show biological properties such as antiviral and antitumor activity, variable effects on the immune system and anticoagulant activity. In addition, some findings provide novel evidence that Polygonatum species may contain potential anti-tumor and anti-viral proteins for possible medical application and large-scale pharmaceutical production. In this review, we focus on the updated research of the chemical constituents of Polygonatum including polysaccharides, steroidal saponins, flavonoids and lectins, and their potential therapeutic roles.

摘要

黄精是一种著名的传统中药,在中国、韩国和日本广泛使用。在过去十年中,已报道了该属植物的成分,包括甾体皂苷、黄酮类、生物碱、木质素、氨基酸和碳水化合物,其中一些具有抗病毒、抗肿瘤活性、对免疫系统的不同作用以及抗凝活性等生物学特性。此外,一些研究结果提供了新的证据,表明黄精属植物可能含有潜在的抗肿瘤和抗病毒蛋白,可用于医学应用和大规模制药生产。在本综述中,我们重点关注黄精化学成分的最新研究,包括多糖、甾体皂苷、黄酮类和凝集素,以及它们的潜在治疗作用。

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