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洗必泰和复方漱口水在降低牙菌斑中变形链球菌数量方面的抗菌效果比较。

Comparison of antimicrobial efficacy of chlorhexidine and combination mouth rinse in reducing the Mutans streptococcus count in plaque.

作者信息

Lakade Laxmi S, Shah Preetam, Shirol Dayanand

机构信息

Assistant Professor, Pediatric and Preventive Dentistry, Bharati Vidyapeeth Deemed University Dental College and Hospital, Pune, Maharashtra, India.

出版信息

J Indian Soc Pedod Prev Dent. 2014 Apr-Jun;32(2):91-6. doi: 10.4103/0970-4388.130780.

Abstract

BACKGROUND

The removal of plaque is utmost important to control dental caries. But in children, factors like lack of dexterity, individual motivation and monitoring limit the effectiveness of tooth brushing. This necessitates the use of chemotherapeutic agents for control of plaque.

AIMS

To compare the antimicrobial efficacy of 0.2% chlorhexidine mouth rinse and mouth rinse containing 0.03% triclosan, 0.05% sodium fluoride, and 5% xylitol in reducing the Mutans streptococcus count in plaque.

MATERIALS AND METHODS

Thirty healthy children aged 8-10 years with dmft (decay component) of three or four were selected. They were divided randomly into two groups: The control or chlorhexidine group and the study group or combination mouth rinse. Both the groups practiced rinsing with respective mouth wash for 1 min for 15 d twice a day. The plaque samples were collected and after incubation Mutans streptococcus count was estimated on the strips from the Dentocult SM kit and evaluated using manufacture's chart.

STATISTICAL ANALYSIS USED

Wilcoxon matched pairs signed ranks test and Mann-Whitney U test were used to analyze the findings.

RESULTS

Statistically significant reduction in the Mutans streptococci count in the plaque was seen in the control and study group from baseline level. But when both the groups were compared, the antimicrobial effect of chlorhexidine was more.

摘要

背景

去除牙菌斑对于控制龋齿至关重要。但对于儿童而言,诸如手部灵活性欠佳、个人积极性及监督等因素限制了刷牙的效果。因此有必要使用化学治疗剂来控制牙菌斑。

目的

比较0.2%洗必泰漱口水与含有0.03%三氯生、0.05%氟化钠和5%木糖醇的漱口水在降低牙菌斑中变形链球菌数量方面的抗菌效果。

材料与方法

选取30名8至10岁、dmft(龋坏部分)为三或四的健康儿童。他们被随机分为两组:对照组或洗必泰组以及研究组或复方漱口水组。两组均使用各自的漱口水每天两次、每次1分钟,持续15天进行漱口。收集牙菌斑样本,培养后使用Dentocult SM试剂盒的试纸条估计变形链球菌数量,并根据制造商的图表进行评估。

所用统计分析方法

采用Wilcoxon配对符号秩检验和Mann-Whitney U检验分析结果。

结果

对照组和研究组的牙菌斑中变形链球菌数量从基线水平均有统计学意义的下降。但两组比较时,洗必泰的抗菌效果更强。

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