Bredewold Obbo W, de Fijter Johan W, Rabelink Ton
Department of Nephrology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
NDT Plus. 2011 Jun;4(3):170-2. doi: 10.1093/ndtplus/sfr038. Epub 2011 Apr 14.
A 38-year-old male was admitted with fever, progressive jaundice, cervical lymphadenopathy, hepatomegaly and acute oliguric renal failure. Epstein-Barr virus (EBV) infection was diagnosed by detection of EBV-DNA in plasma and confirmed by EBV seroconversion. Kidney biopsy revealed acute tubular necrosis and abundant casts, consisting of bilirubin pigment. With conservative treatment, the patient fully recovered from cholemic nephrosis, an uncommon condition, not described after EBV infection before.
一名38岁男性因发热、进行性黄疸、颈部淋巴结肿大、肝肿大及急性少尿性肾衰竭入院。通过检测血浆中的EBV-DNA诊断为EB病毒(EBV)感染,并通过EBV血清转化得到证实。肾脏活检显示急性肾小管坏死和大量由胆红素色素组成的管型。经过保守治疗,患者从胆血症性肾病中完全康复,这是一种罕见的病症,此前在EBV感染后未曾有过描述。