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中国上海生活垃圾焚烧厂周边PM<0.2、PM0.2 - 2.5和PM2.5 - 10的特性及细胞毒性

Characterization and Cytotoxicity of PM<0.2, PM0.2-2.5 and PM2.5-10 around MSWI in Shanghai, China.

作者信息

Cao Lingling, Zeng Jianrong, Liu Ke, Bao Liangman, Li Yan

机构信息

Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.

School of Physics, University of Chinese Academy of Sciences, Beijing 100049, China.

出版信息

Int J Environ Res Public Health. 2015 May 12;12(5):5076-89. doi: 10.3390/ijerph120505076.

DOI:10.3390/ijerph120505076
PMID:25985309
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4454955/
Abstract

BACKGROUND

The potential impact of municipal solid waste incineration (MSWI), which is an anthropogenic source of aerosol emissions, is of great public health concern. This study investigated the characterization and cytotoxic effects of ambient ultrafine particles (PM<0.2), fine particles (PM0.2-2.5) and coarse particles (PM2.5-10) collected around a municipal solid waste incineration (MSWI) plant in the Pudong district of Shanghai.

METHODS

Mass concentrations of trace elements in particulate matter (PM) samples were determined using ICP-MS (Inductively Coupled Plasma Mass Spectrometry). The cytotoxicity of sampled atmospheric PM was evaluated by cell viability and reactive oxygen species (ROS) levels in A549 cells.

RESULT

The mass percentage of PM0.2-2.5 accounted for 72.91% of the total mass of PM. Crustal metals (Mg, Al, and Ti) were abundant in the coarse particles, while the anthropogenic elements (V, Ni, Cu, Zn, Cd, and Pb) were dominant in the fine particles. The enrichment factors of Zn, Cd and Pb in the fine and ultrafine particles were extremely high (>100). The cytotoxicity of the size-resolved particles was in the order of coarse particles < fine particles < ultrafine particles.

CONCLUSIONS

Fine particles dominated the MSWI ambient particles. Emissions from the MSWI could bring contamination of anthropogenic elements (Zn, Cd and Pb) into ambient environment. The PM around the MSWI plant displayed an additive toxic effect, and the ultrafine and fine particles possessed higher biological toxicity than the coarse particles.

摘要

背景

城市固体废弃物焚烧（MSWI）作为气溶胶排放的人为来源，其潜在影响备受公众健康关注。本研究调查了在上海浦东新区一座城市固体废弃物焚烧（MSWI）厂周边采集的环境超细颗粒物（PM<0.2）、细颗粒物（PM0.2 - 2.5）和粗颗粒物（PM2.5 - 10）的特征及细胞毒性效应。

方法

采用电感耦合等离子体质谱法（ICP - MS）测定颗粒物（PM）样品中微量元素的质量浓度。通过A549细胞的细胞活力和活性氧（ROS）水平评估采集的大气PM的细胞毒性。

结果

PM0.2 - 2.5的质量百分比占PM总质量的72.91%。地壳金属（Mg、Al和Ti）在粗颗粒物中含量丰富，而人为源元素（V、Ni、Cu、Zn、Cd和Pb）在细颗粒物中占主导地位。细颗粒物和超细颗粒物中Zn、Cd和Pb的富集因子极高（>100）。粒径分辨颗粒物细胞毒性大小顺序为粗颗粒物<细颗粒物<超细颗粒物。

结论

细颗粒物在MSWI周边环境颗粒物中占主导。MSWI排放可将人为源元素（Zn、Cd和Pb）污染带入周边环境。MSWI厂周边的PM呈现出相加毒性效应，超细颗粒物和细颗粒物比粗颗粒物具有更高的生物毒性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/0ce31d97210c/ijerph-12-05076-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/18158acb0fcb/ijerph-12-05076-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/de5bd59e3dcb/ijerph-12-05076-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/8cf9ecec6ab6/ijerph-12-05076-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/f5fc2dbff58f/ijerph-12-05076-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/0ce31d97210c/ijerph-12-05076-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/18158acb0fcb/ijerph-12-05076-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/de5bd59e3dcb/ijerph-12-05076-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/8cf9ecec6ab6/ijerph-12-05076-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/f5fc2dbff58f/ijerph-12-05076-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6226/4454955/0ce31d97210c/ijerph-12-05076-g005.jpg

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本文引用的文献

1
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Int J Environ Res Public Health. 2015 Feb 13;12(2):2090-104. doi: 10.3390/ijerph120202090.
2
Distribution of graphene oxide and TiO2-graphene oxide composite in A549 cells.氧化石墨烯和二氧化钛-氧化石墨烯复合材料在A549细胞中的分布。
Biol Trace Elem Res. 2014 Jun;159(1-3):393-8. doi: 10.1007/s12011-014-0027-3. Epub 2014 May 30.
3
Int J Environ Res Public Health. 2017 Nov 25;14(12):1458. doi: 10.3390/ijerph14121458.
4
Direct Quantification of Rare Earth Elements Concentrations in Urine of Workers Manufacturing Cerium, Lanthanum Oxide Ultrafine and Nanoparticles by a Developed and Validated ICP-MS.通过已开发并验证的电感耦合等离子体质谱法直接定量测定制造氧化铈、氧化镧超细颗粒和纳米颗粒的工人尿液中的稀土元素浓度。
Int J Environ Res Public Health. 2016 Mar 22;13(3):350. doi: 10.3390/ijerph13030350.
Effects of fullerene C₆₀ nanoparticles on A549 cells.
富勒烯C₆₀纳米颗粒对A549细胞的影响。
Environ Toxicol Pharmacol. 2014 Mar;37(2):656-61. doi: 10.1016/j.etap.2014.01.015. Epub 2014 Feb 5.
4
PM2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells.PM2.5 诱导的氧化应激触发人肺上皮 A549 细胞自噬。
Toxicol In Vitro. 2013 Sep;27(6):1762-70. doi: 10.1016/j.tiv.2013.05.004. Epub 2013 May 17.
5
Characterization of cytotoxicity of airborne particulates from urban areas of Lahore.大气颗粒物对拉合尔市区细胞毒性的特征分析。
J Environ Sci (China). 2012;24(11):2028-34. doi: 10.1016/s1001-0742(11)61040-1.
6
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Cell Biol Toxicol. 2013 Jun;29(3):143-57. doi: 10.1007/s10565-013-9242-5. Epub 2013 Mar 24.
7
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Environ Sci Technol. 2012 Sep 18;46(18):10364-71. doi: 10.1021/es302343s. Epub 2012 Sep 4.
8
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Environ Toxicol. 2013 Feb;28(2):76-86. doi: 10.1002/tox.20699. Epub 2011 Mar 7.
9
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Eur Rev Med Pharmacol Sci. 2010 Oct;14(10):809-21.
10
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