Dumville Jo C, Keogh Samantha J, Liu Zhenmi, Stubbs Nikki, Walker Rachel M, Fortnam Mathew
School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK, M13 9PL.
Cochrane Database Syst Rev. 2015 May 21;2015(5):CD011277. doi: 10.1002/14651858.CD011277.pub2.
Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and there are many options to choose from including alginate dressings. A clear and current overview of current evidence is required to facilitate decision-making regarding dressing use for the treatment of pressure ulcers. This review is part of a suite of Cochrane reviews investigating the use of dressings in the treatment of pressure ulcers. Each review will focus on a particular dressing type.
To assess the effects of alginate dressings for treating pressure ulcers in any care setting.
For this review, in April 2015 we searched the following databases the Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL. There were no restrictions based on language or date of publication.
Published or unpublished randomised controlled trials (RCTs) comparing the effects of alginate with alternative wound dressings or no dressing in the treatment of pressure ulcers (stage II or above).
Two review authors independently performed study selection, risk of bias assessment and data extraction.
We included six studies (336 participants) in this review; all studies had two arms. The included studies compared alginate dressings with six other interventions that included: hydrocolloid dressings, silver containing alginate dressings, and radiant heat therapy. Each of the six comparisons included just one study and these had limited participant numbers and short follow-up times. All the evidence was of low or very low quality. Where data were available there was no evidence of a difference between alginate dressings and alternative treatments in terms of complete wound healing or adverse events.
AUTHORS' CONCLUSIONS: The relative effects of alginate dressings compared with alternative treatments are unclear. The existing trials are small, of short duration and at risk of bias. Decision makers may wish to consider aspects such as cost of dressings and the wound management properties offered by each dressing type, for example, exudate management.
压疮,也被称为褥疮、卧疮和压力性损伤,是皮肤或其下组织或两者的局部损伤区域。敷料被广泛用于治疗压疮,有许多选择,包括藻酸盐敷料。需要一份清晰且最新的现有证据综述,以促进关于用于治疗压疮的敷料使用的决策。本综述是一组Cochrane综述的一部分,这些综述调查敷料在治疗压疮中的使用情况。每项综述将聚焦于一种特定的敷料类型。
评估藻酸盐敷料在任何护理环境中治疗压疮的效果。
对于本综述,我们在2015年4月检索了以下数据库:Cochrane伤口小组专业注册库;Cochrane对照试验中央注册库(CENTRAL)(Cochrane图书馆);Ovid MEDLINE;Ovid MEDLINE(在研及其他非索引引文);Ovid EMBASE;以及EBSCO CINAHL。没有基于语言或出版日期的限制。
比较藻酸盐与其他伤口敷料或不使用敷料在治疗压疮(II期或以上)中的效果的已发表或未发表的随机对照试验(RCT)。
两位综述作者独立进行研究选择、偏倚风险评估和数据提取。
我们在本综述中纳入了六项研究(336名参与者);所有研究均有两个组。纳入的研究将藻酸盐敷料与其他六种干预措施进行了比较,这些干预措施包括:水胶体敷料、含银藻酸盐敷料和辐射热疗法。六项比较中的每一项都只包括一项研究,且这些研究的参与者数量有限,随访时间较短。所有证据的质量都很低或非常低。在有数据的情况下,没有证据表明藻酸盐敷料与替代治疗在完全伤口愈合或不良事件方面存在差异。
与替代治疗相比,藻酸盐敷料的相对效果尚不清楚。现有的试验规模小、持续时间短且存在偏倚风险。决策者可能希望考虑诸如敷料成本和每种敷料类型所提供的伤口管理特性(例如渗出液管理)等方面。