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本文引用的文献

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Point prevalence of complex wounds in a defined United Kingdom population.英国特定人群中复杂伤口的现患率。
Wound Repair Regen. 2014 Nov-Dec;22(6):694-700. doi: 10.1111/wrr.12230. Epub 2015 Jan 8.
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Tissue changes in patients following spinal cord injury and implications for wheelchair cushions and tissue loading: a literature review.脊髓损伤患者的组织变化及其对轮椅坐垫和组织负荷的影响:文献综述
Ostomy Wound Manage. 2014 Feb;60(2):34-45.
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A multi-center, randomized, clinical trial comparing adhesive polyurethane foam dressing and adhesive hydrocolloid dressing in patients with grade II pressure ulcers in primary care and nursing homes.一项多中心、随机、临床试验,比较初级保健和养老院中 II 级压力性溃疡患者使用粘性聚氨酯泡沫敷料和粘性水胶体敷料的效果。
BMC Fam Pract. 2013 Dec 21;14:196. doi: 10.1186/1471-2296-14-196.
4
Cost-effectiveness analysis in comparing alginate silver dressing with silver zinc sulfadiazine cream in the treatment of pressure ulcers.藻酸盐银敷料与磺胺嘧啶银锌乳膏治疗压疮的成本效益分析
Arch Plast Surg. 2013 Sep;40(5):589-96. doi: 10.5999/aps.2013.40.5.589. Epub 2013 Sep 13.
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A re-analysis of the Cochrane Library data: the dangers of unobserved heterogeneity in meta-analyses.对考科蓝图书馆数据的重新分析:荟萃分析中未观察到的异质性的危险。
PLoS One. 2013 Jul 26;8(7):e69930. doi: 10.1371/journal.pone.0069930. Print 2013.
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Pressure ulcer treatment strategies: a systematic comparative effectiveness review.压力性溃疡治疗策略:系统比较有效性评价。
Ann Intern Med. 2013 Jul 2;159(1):39-50. doi: 10.7326/0003-4819-159-1-201307020-00007.
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The prevalence of pressure ulcers in community settings: an observational study.社区环境中压疮的流行情况:一项观察性研究。
Int J Nurs Stud. 2013 Nov;50(11):1550-7. doi: 10.1016/j.ijnurstu.2013.04.001. Epub 2013 Jun 10.
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What is the NHS Safety Thermometer?什么是国民保健服务安全温度计?
Clin Risk. 2012 Sep;18(5):163-169. doi: 10.1258/cr.2012.012038.
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The cost of pressure ulcers in the United Kingdom.英国压疮的成本。
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10
Randomised controlled trial evaluating the efficacy of wrap therapy for wound healing acceleration in patients with NPUAP stage II and III pressure ulcer.一项随机对照试验,评估包裹疗法对NPUAP II期和III期压疮患者伤口愈合加速的疗效。
BMJ Open. 2012 Jan 5;2(1):e000371. doi: 10.1136/bmjopen-2011-000371. Print 2012.

用于治疗压疮的藻酸盐敷料。

Alginate dressings for treating pressure ulcers.

作者信息

Dumville Jo C, Keogh Samantha J, Liu Zhenmi, Stubbs Nikki, Walker Rachel M, Fortnam Mathew

机构信息

School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK, M13 9PL.

出版信息

Cochrane Database Syst Rev. 2015 May 21;2015(5):CD011277. doi: 10.1002/14651858.CD011277.pub2.

DOI:10.1002/14651858.CD011277.pub2
PMID:25994366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10555387/
Abstract

BACKGROUND

Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and there are many options to choose from including alginate dressings. A clear and current overview of current evidence is required to facilitate decision-making regarding dressing use for the treatment of pressure ulcers. This review is part of a suite of Cochrane reviews investigating the use of dressings in the treatment of pressure ulcers. Each review will focus on a particular dressing type.

OBJECTIVES

To assess the effects of alginate dressings for treating pressure ulcers in any care setting.

SEARCH METHODS

For this review, in April 2015 we searched the following databases the Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL. There were no restrictions based on language or date of publication.

SELECTION CRITERIA

Published or unpublished randomised controlled trials (RCTs) comparing the effects of alginate with alternative wound dressings or no dressing in the treatment of pressure ulcers (stage II or above).

DATA COLLECTION AND ANALYSIS

Two review authors independently performed study selection, risk of bias assessment and data extraction.

MAIN RESULTS

We included six studies (336 participants) in this review; all studies had two arms. The included studies compared alginate dressings with six other interventions that included: hydrocolloid dressings, silver containing alginate dressings, and radiant heat therapy. Each of the six comparisons included just one study and these had limited participant numbers and short follow-up times. All the evidence was of low or very low quality. Where data were available there was no evidence of a difference between alginate dressings and alternative treatments in terms of complete wound healing or adverse events.

AUTHORS' CONCLUSIONS: The relative effects of alginate dressings compared with alternative treatments are unclear. The existing trials are small, of short duration and at risk of bias. Decision makers may wish to consider aspects such as cost of dressings and the wound management properties offered by each dressing type, for example, exudate management.

摘要

背景

压疮,也被称为褥疮、卧疮和压力性损伤,是皮肤或其下组织或两者的局部损伤区域。敷料被广泛用于治疗压疮,有许多选择,包括藻酸盐敷料。需要一份清晰且最新的现有证据综述,以促进关于用于治疗压疮的敷料使用的决策。本综述是一组Cochrane综述的一部分,这些综述调查敷料在治疗压疮中的使用情况。每项综述将聚焦于一种特定的敷料类型。

目的

评估藻酸盐敷料在任何护理环境中治疗压疮的效果。

检索方法

对于本综述,我们在2015年4月检索了以下数据库:Cochrane伤口小组专业注册库;Cochrane对照试验中央注册库(CENTRAL)(Cochrane图书馆);Ovid MEDLINE;Ovid MEDLINE(在研及其他非索引引文);Ovid EMBASE;以及EBSCO CINAHL。没有基于语言或出版日期的限制。

选择标准

比较藻酸盐与其他伤口敷料或不使用敷料在治疗压疮(II期或以上)中的效果的已发表或未发表的随机对照试验(RCT)。

数据收集与分析

两位综述作者独立进行研究选择、偏倚风险评估和数据提取。

主要结果

我们在本综述中纳入了六项研究(336名参与者);所有研究均有两个组。纳入的研究将藻酸盐敷料与其他六种干预措施进行了比较,这些干预措施包括:水胶体敷料、含银藻酸盐敷料和辐射热疗法。六项比较中的每一项都只包括一项研究,且这些研究的参与者数量有限,随访时间较短。所有证据的质量都很低或非常低。在有数据的情况下,没有证据表明藻酸盐敷料与替代治疗在完全伤口愈合或不良事件方面存在差异。

作者结论

与替代治疗相比,藻酸盐敷料的相对效果尚不清楚。现有的试验规模小、持续时间短且存在偏倚风险。决策者可能希望考虑诸如敷料成本和每种敷料类型所提供的伤口管理特性(例如渗出液管理)等方面。