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用于伤口敷料的生物医学材料：最新进展与应用

Biomedical materials for wound dressing: recent advances and applications.

作者信息

Nguyen Hien Minh, Ngoc Le Tam Thi, Nguyen An Thanh, Thien Le Han Nguyen, Pham Thi Tan

机构信息

School of Medicine, Vietnam National University Ho Chi Minh City Ho Chi Minh City Vietnam

Ho Chi Minh City University of Technology (HCMUT), Vietnam National University Ho Chi Minh City Ho Chi Minh City Vietnam

出版信息

RSC Adv. 2023 Feb 13;13(8):5509-5528. doi: 10.1039/d2ra07673j. eCollection 2023 Feb 6.

DOI:10.1039/d2ra07673j
PMID:36793301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9924226/
Abstract

Wound healing is vital to maintain the physiological functions of the skin. The most common treatment is the use of a dressing to cover the wound and reduce infection risk and the rate of secondary injuries. Modern wound dressings have been the top priority choice for healing various types of wounds owing to their outstanding biocompatibility and biodegradability. In addition, they also maintain temperature and a moist environment, aid in pain relief, and improve hypoxic environments to stimulate wound healing. Due to the different types of wounds, as well as the variety of advanced wound dressing products, this review will provide information on the clinical characteristics of the wound, the properties of common modern dressings, and the , as well as the clinical trials on their effectiveness. The most popular types commonly used in producing modern dressings are hydrogels, hydrocolloids, alginates, foams, and films. In addition, the review also presents the polymer materials for dressing applications as well as the trend of developing these current modern dressings to maximize their function and create ideal dressings. The last is the discussion about dressing selection in wound treatment and an estimate of the current development tendency of new materials for wound healing dressings.

摘要

伤口愈合对于维持皮肤的生理功能至关重要。最常见的治疗方法是使用敷料覆盖伤口，以降低感染风险和二次受伤率。现代伤口敷料因其出色的生物相容性和生物降解性，已成为治疗各类伤口的首选。此外，它们还能保持温度和湿润环境，缓解疼痛，并改善缺氧环境以促进伤口愈合。由于伤口类型不同，以及先进伤口敷料产品种类繁多，本综述将提供有关伤口的临床特征、常见现代敷料的特性，以及它们有效性的临床试验等信息。生产现代敷料最常用的类型是水凝胶、水胶体、藻酸盐、泡沫和薄膜。此外，综述还介绍了用于敷料应用的聚合物材料，以及当前这些现代敷料的发展趋势，以最大限度地发挥其功能并创造理想的敷料。最后是关于伤口治疗中敷料选择的讨论，以及对伤口愈合敷料新材料当前发展趋势的估计。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29b7/9924226/7cac7aeb45a2/d2ra07673j-f7.jpg
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