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关闭Mad2循环。

Closing the Mad2 cycle.

作者信息

Musacchio Andrea

机构信息

Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany and the Centre for Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany.

出版信息

Elife. 2015 May 22;4:e08283. doi: 10.7554/eLife.08283.

DOI:10.7554/eLife.08283
PMID:25997937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4439612/
Abstract

Chromosome separation is regulated by a cycle that involves a protein undergoing an unusual topological conversion.

摘要

染色体分离由一个循环调控,该循环涉及一种经历异常拓扑转换的蛋白质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c281/4439612/0fde641caca8/elife08283f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c281/4439612/0fde641caca8/elife08283f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c281/4439612/0fde641caca8/elife08283f001.jpg

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本文引用的文献

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Elife. 2015 Apr 28;4:e07367. doi: 10.7554/eLife.07367.
2
Pch2(TRIP13): controlling cell division through regulation of HORMA domains.Pch2(TRIP13):通过调控HORMA结构域来控制细胞分裂。
Chromosoma. 2015 Sep;124(3):333-9. doi: 10.1007/s00412-015-0516-y. Epub 2015 Apr 21.
3
The chromosome axis controls meiotic events through a hierarchical assembly of HORMA domain proteins.染色体轴通过 HORMA 结构域蛋白的层次组装来控制减数分裂事件。
细胞周期检查点对有丝分裂后期的调控:来自. 的启示。
Genes (Basel). 2020 Feb 12;11(2):195. doi: 10.3390/genes11020195.
4
Chromosome integrity checkpoints in stem and progenitor cells: transitions upon differentiation, pathogenesis, and aging.干细胞和祖细胞中的染色体完整性检查点:分化、发病机制和衰老时的转变。
Cell Mol Life Sci. 2018 Oct;75(20):3771-3779. doi: 10.1007/s00018-018-2891-z. Epub 2018 Jul 31.
5
The mitotic checkpoint complex (MCC): looking back and forth after 15 years.有丝分裂检查点复合物(MCC):十五年后的回顾与展望
AIMS Mol Sci. 2016;3(4):597-634. doi: 10.3934/molsci.2016.4.597. Epub 2016 Oct 24.
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Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II.钙离子/钙调蛋白依赖的蛋白激酶 II 的激活触发亚基交换的分子机制。
Elife. 2016 Mar 7;5:e13405. doi: 10.7554/eLife.13405.
Dev Cell. 2014 Nov 24;31(4):487-502. doi: 10.1016/j.devcel.2014.09.013. Epub 2014 Nov 6.
4
Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31(comet).由 AAA-ATP 酶 TRIP13 和 p31(comet)的联合作用将有丝分裂检查点复合物解体。
Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12019-24. doi: 10.1073/pnas.1412901111. Epub 2014 Aug 4.
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6
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7
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