Bicer Senol, Kuyrukluyildiz Ufuk, Akyol Fethi, Sahin Murat, Binici Orhan, Onk Didem
Department of Pediatric Surgery, Erzincan University of Medical Sciences, Erzincan, Turkey.
Department of Anesthesiology, Erzincan University of Medical Sciences, Erzincan, Turkey.
Iran Red Crescent Med J. 2015 Mar 20;17(3):e26258. doi: 10.5812/ircmj.26258. eCollection 2015 Mar.
Although male circumcision is a surgical intervention that is frequently performed in children, there is no consensus about the age at which it should be performed.
The purpose of this study was to determine the best age range for routine male circumcision with respect to a child's health and the cost.
This clinical trial was conducted in the affiliated hospital of the Erzincan University of Medical Sciences, Turkey, in 2014. The circumcised children were evaluated in 3 groups: < 1 year old (Group 1), 1-7 years old (Group 2), and > 7 years old (Group 3). To obtain a satisfactory Wilton sedation score, midazolam 0.1 mg/kg IV was administered first. If adequate sedation was not achieved, ketamine 2 mg/kg IV was also administered. If adequate sedation was still not achieved, general anesthesia was administered via a laryngeal mask. At the end of the surgery, the groups were compared in terms of post-anesthesia recovery duration, complications, discharging duration, and cost.
A total of 603 children were circumcised, 374 in Group 1, 94 in Group 2, and 135 in Group 3. Midazolam was sufficient for sedation in 364 Group 1 patients (97.3%), 6 Group 2 patients (6.3%), and 38 Group 3 patients (28.1%). The shortest post-anesthesia recovery duration after surgical intervention and time until discharge, the lowest cost, and the fewest anesthesia complications were observed in Group 1 (P < 0.05 for all).
Although almost all of the < 1 year-old children could be sedated with midazolam alone, most of the > 1 year-old children required ketamine or general anesthesia. Performing circumcision when children are less than 1 year old decreases the risk of complications due to anesthesia and lowers the costs compared with performing the procedure on older children.
尽管男性包皮环切术是一种常在儿童中进行的外科手术,但对于该手术应在何年龄进行尚无共识。
本研究的目的是确定就儿童健康和成本而言,常规男性包皮环切术的最佳年龄范围。
本临床试验于2014年在土耳其埃尔津詹大学医学科学附属医院进行。接受包皮环切术的儿童分为3组:<1岁(第1组)、1 - 7岁(第2组)和>7岁(第3组)。为获得满意的威尔顿镇静评分,首先静脉注射咪达唑仑0.1 mg/kg。若未达到充分镇静,则静脉注射氯胺酮2 mg/kg。若仍未达到充分镇静,则通过喉罩给予全身麻醉。手术结束时,比较各组的麻醉后恢复持续时间、并发症、出院持续时间和成本。
共有603名儿童接受了包皮环切术,第1组374名,第2组94名,第3组135名。咪达唑仑对364名第1组患者(97.3%)、6名第2组患者(6.3%)和38名第3组患者(28.1%)的镇静效果足够。第1组观察到手术干预后最短的麻醉后恢复持续时间和出院时间、最低的成本以及最少的麻醉并发症(所有P < 0.05)。
尽管几乎所有<1岁的儿童仅用咪达唑仑即可镇静,但大多数>1岁的儿童需要氯胺酮或全身麻醉。与对年龄较大的儿童进行该手术相比,在儿童小于1岁时进行包皮环切术可降低麻醉并发症的风险并降低成本。