Lin K, Lloyd-Jones D M, Li D, Liu Y, Yang J, Markl M, Carr J C
Department of Radiology, Northwestern University, Chicago, IL, USA
Department of Preventive Medicine, Northwestern University, Chicago, IL, USA.
Lupus. 2015 Oct;24(11):1126-34. doi: 10.1177/0961203315588577. Epub 2015 Jun 2.
In the long-term survival of patients with systemic lupus erythematosus (SLE), cardiovascular disease (CVD) is a leading cause of death. Recently, multimodality cardiovascular imaging methods have been adopted for the evaluation of cardiovascular risk, which has shown to be associated with both traditional cardiovascular risk factors and SLE-specific conditions. Quantitative imaging biomarkers, which can describe both morphological and functional abnormalities in the heart, are expected to provide new insights to stratify cardiovascular risks and to guide SLE management by assessing individual responses to therapies either protecting the cardiovascular system or suppressing the autoimmune reactions. In this review, we will discuss cutting-edge cardiovascular imaging techniques and potential clinical applications and limitations of those techniques for the evaluation of major SLE-related heart disorders.
在系统性红斑狼疮（SLE）患者的长期生存中，心血管疾病（CVD）是主要死因。近来，多模态心血管成像方法已被用于评估心血管风险，该风险已显示与传统心血管危险因素及SLE特异性病症均相关。定量成像生物标志物能够描述心脏的形态和功能异常，有望通过评估个体对保护心血管系统或抑制自身免疫反应的治疗的反应，为分层心血管风险及指导SLE管理提供新见解。在本综述中，我们将讨论前沿心血管成像技术及其在评估主要SLE相关心脏疾病方面的潜在临床应用和局限性。
