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佛蒙特州东部马脑炎的首次爆发:疫情描述及病毒分离株的系统发育关系

The first outbreak of eastern equine encephalitis in Vermont: outbreak description and phylogenetic relationships of the virus isolate.

作者信息

Saxton-Shaw Kali D, Ledermann Jeremy P, Kenney Joan L, Berl Erica, Graham Alan C, Russo Joel M, Powers Ann M, Mutebi John-Paul

机构信息

Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, Fort Collins, Colorado, United States of America.

Vermont Department of Health, Burlington, Vermont, United States of America.

出版信息

PLoS One. 2015 Jun 4;10(6):e0128712. doi: 10.1371/journal.pone.0128712. eCollection 2015.

DOI:10.1371/journal.pone.0128712
PMID:26043136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4455994/
Abstract

The first known outbreak of eastern equine encephalitis (EEE) in Vermont occurred on an emu farm in Rutland County in 2011. The first isolation of EEE virus (EEEV) in Vermont (VT11) was during this outbreak. Phylogenetic analysis revealed that VT11 was most closely related to FL01, a strain from Florida isolated in 2001, which is both geographically and temporally distinct from VT11. EEEV RNA was not detected in any of the 3,905 mosquito specimens tested, and the specific vectors associated with this outbreak are undetermined.

摘要

佛蒙特州首次有记录的东部马脑炎(EEE)疫情于2011年发生在拉特兰县的一个鸸鹋养殖场。佛蒙特州首次分离出的EEE病毒(VT11)就是在此次疫情期间。系统发育分析显示,VT11与2001年从佛罗里达州分离出的毒株FL01关系最为密切,FL01在地理和时间上都与VT11不同。在检测的3905份蚊子标本中均未检测到EEE病毒RNA,与此次疫情相关的具体传播媒介尚未确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43c/4455994/50c9a21742db/pone.0128712.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43c/4455994/cb4363b43bd4/pone.0128712.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43c/4455994/50c9a21742db/pone.0128712.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43c/4455994/cb4363b43bd4/pone.0128712.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43c/4455994/50c9a21742db/pone.0128712.g002.jpg

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