Khalilzadeh Saeedhossein, Afkhami-Ardekani Mohammad, Afrand Mohammadhosain
Assistant Professor, Department of Endocrinology, Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Professor, Department of Endocrinology, Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Electron Physician. 2015 Mar 1;7(1):998-1004. doi: 10.14661/2015.998-1004. eCollection 2015 Jan-Mar.
The prevalence of type 2 diabetes mellitus (T2DM) varies among ethnic groups. We aimed to estimate the prevalence of diagnosed and undiagnosed diabetes mellitus, impaired fasting glucose (IFG), and impaired glucose tolerance (IGT) for the first time in an ethnic population, specifically Zoroastrian citizens in Yazd, Iran whose ages were 30 or older.
In a cross-sectional study, participants aged≥30 years were selected using systematic random sampling. An inventory, including socio-demographic data, was completed. Weight, height, body mass index (BMI), and blood pressure (BP) were measured using standard methods. Also, blood levels of glucose, triglycerides (TG), total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), urea, creatinine (Cr), and uric acid were measured. The latest criteria established by the American Diabetes Association (ADA) were used to diagnose DM.
The mean age of the participants (n=403) was 56.9±12.8 years. The total prevalence of diabetes, including previously diagnosed and undiagnosed diabetes, IFG, and IGT was 26.1%, 18.6%, 7.5%, 34.7% and 25.8%, respectively. Participants with diabetes had higher fasting blood sugar (FBS) (P<0.001), oral glucose tolerance test (OGTT) (P<0.001), urea (P=0.019), BMI (P=0.001), systolic blood pressures (P<0.001), TG (P=0.007) and lower HDL (P=0.034) than patients with IFG, IGT, and normoglycemic subjects.
The current study showed a high prevalence of T2DM in the Zoroastrian population of Yazd, Iran. One-third of the total cases with diabetes were undiagnosed.
2型糖尿病（T2DM）的患病率在不同种族群体中有所差异。我们旨在首次估算伊朗亚兹德地区年龄在30岁及以上的琐罗亚斯德教公民这一特定种族人群中已诊断和未诊断的糖尿病、空腹血糖受损（IFG）和糖耐量受损（IGT）的患病率。
在一项横断面研究中，采用系统随机抽样法选取年龄≥30岁的参与者。完成一份包括社会人口统计学数据的调查问卷。使用标准方法测量体重、身高、体重指数（BMI）和血压（BP）。此外，还测量了血糖、甘油三酯（TG）、总胆固醇（TC）、高密度脂蛋白（HDL）、低密度脂蛋白（LDL）、尿素、肌酐（Cr）和尿酸的血液水平。采用美国糖尿病协会（ADA）制定的最新标准诊断糖尿病。
参与者（n = 403）的平均年龄为56.9±12.8岁。糖尿病（包括先前诊断和未诊断的糖尿病）、IFG和IGT的总患病率分别为26.1%、18.6%、7.5%、34.7%和25.8%。与IFG、IGT患者和血糖正常的受试者相比，糖尿病患者的空腹血糖（FBS）（P<0.001）、口服葡萄糖耐量试验（OGTT）（P<0.001）、尿素（P = 0.019）、BMI（P = 0.001）、收缩压（P<0.001）、TG（P = 0.007）更高，而HDL更低（P = 0.034）。
当前研究表明，伊朗亚兹德的琐罗亚斯德教人群中T2DM患病率较高。糖尿病患者中有三分之一未被诊断出来。
