Choudhury Manash Kumar, Shiferaw Yoseph, Hussen Ahmed
Department of Chemistry, The School of Postgraduate Studies, Dilla University, P.O. Box 419, Dilla, Ethiopia.
J Parasit Dis. 2015 Jun;39(2):298-302. doi: 10.1007/s12639-013-0311-8. Epub 2013 Jul 12.
The in vitro toxicity of Millettia ferruginea darasana (family: Fabaceae) was tested against the larvae adult male and female of a three-host tick, Amblyomma variegatum Fabricius (family: Ixodidae or hard tick), known as 'tropical bont tick' parasitic mainly to cattle found in Ethiopia and other equatorial Africa. The 20, 40, 60, 80 and 100 % concentrations of the seed oil extracted with petroleum ether were found to kill all (100 % mortality) larvae after 12, 9, 6, 3 and 1.5 h respectively. The results summarized in the Table 1 was found to be statistically significant at the probability level of p = 0.05. The 100 % concentration of the oil caused 100 % mortality of adult male, adult female and fully engorged female tick after 5, 7 and 12 h respectively. The root and root bark showed less toxicity. The leaves did not show any toxicity. [Table: see text].
对豆科植物铁锈崖豆藤（Millettia ferruginea darasana）的体外毒性进行了测试，受试对象为一种三宿主蜱——变异革蜱（Amblyomma variegatum Fabricius，蜱螨目硬蜱科）的幼虫、成年雄蜱和成年雌蜱，这种蜱俗称“热带牛蜱”，主要寄生于埃塞俄比亚和其他赤道非洲地区的牛身上。结果发现，用石油醚提取的该植物种子油浓度为20%、40%、60%、80%和100%时，分别在12小时、9小时、6小时、3小时和1.5小时后杀死了所有（100%死亡率）幼虫。表1总结的结果在概率水平p = 0.05时具有统计学意义。该植物种子油浓度为100%时，分别在5小时、7小时和12小时后导致成年雄蜱、成年雌蜱和饱血雌蜱的死亡率达到100%。根和根皮的毒性较小。叶子未显示出任何毒性。[见表文]
