Tsujimura Koji, Murase Harutaka, Bannai Hiroshi, Nemoto Manabu, Yamanaka Takashi, Kondo Takashi
Epizootic Research Center, Equine Research Institute, Japan Racing Association,1400-4 Shiba, Shimotsuke, Tochigi 329-0412, Japan.
J Vet Med Sci. 2015 Nov;77(11):1545-8. doi: 10.1292/jvms.15-0030. Epub 2015 Jun 14.
We investigated the influences of various reaction conditions on equine herpesvirus type 1 (EHV-1) disinfection by 5 commercial disinfectants (3 quaternary ammonium compounds [QACs] and 2 chlorine-based disinfectants) and 1 anionic surfactant. QACs at their highest recommended concentrations had no virucidal effect on EHV-1 with a 10-min reaction time at 0°C or a 1-min reaction time at room temperature. Chlorine-based disinfectants achieved EHV-1 disinfection with a 10-min reaction time at -10°C or a 30-sec reaction time at room temperature. In the presence of 5% fetal bovine serum, QACs (except for benzalkonium chloride) showed more stable virucidal effects than did chlorine-based disinfectants. The virucidal effect of the anionic surfactant was almost equivalent to that of the QACs.
我们研究了各种反应条件对5种市售消毒剂(3种季铵化合物[QACs]和2种氯基消毒剂)以及1种阴离子表面活性剂对1型马疱疹病毒(EHV-1)消毒效果的影响。在0°C下反应10分钟或室温下反应1分钟时,处于最高推荐浓度的QACs对EHV-1没有杀病毒作用。氯基消毒剂在-10°C下反应10分钟或室温下反应30秒时可实现对EHV-1的消毒。在5%胎牛血清存在的情况下,QACs(除苯扎氯铵外)比氯基消毒剂表现出更稳定的杀病毒效果。阴离子表面活性剂的杀病毒效果几乎与QACs相当。