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五种市售消毒剂和一种阴离子表面活性剂对1型马疱疹病毒的疗效

Efficacy of five commercial disinfectants and one anionic surfactant against equine herpesvirus type 1.

作者信息

Tsujimura Koji, Murase Harutaka, Bannai Hiroshi, Nemoto Manabu, Yamanaka Takashi, Kondo Takashi

机构信息

Epizootic Research Center, Equine Research Institute, Japan Racing Association,1400-4 Shiba, Shimotsuke, Tochigi 329-0412, Japan.

出版信息

J Vet Med Sci. 2015 Nov;77(11):1545-8. doi: 10.1292/jvms.15-0030. Epub 2015 Jun 14.

Abstract

We investigated the influences of various reaction conditions on equine herpesvirus type 1 (EHV-1) disinfection by 5 commercial disinfectants (3 quaternary ammonium compounds [QACs] and 2 chlorine-based disinfectants) and 1 anionic surfactant. QACs at their highest recommended concentrations had no virucidal effect on EHV-1 with a 10-min reaction time at 0°C or a 1-min reaction time at room temperature. Chlorine-based disinfectants achieved EHV-1 disinfection with a 10-min reaction time at -10°C or a 30-sec reaction time at room temperature. In the presence of 5% fetal bovine serum, QACs (except for benzalkonium chloride) showed more stable virucidal effects than did chlorine-based disinfectants. The virucidal effect of the anionic surfactant was almost equivalent to that of the QACs.

摘要

我们研究了各种反应条件对5种市售消毒剂(3种季铵化合物[QACs]和2种氯基消毒剂)以及1种阴离子表面活性剂对1型马疱疹病毒(EHV-1)消毒效果的影响。在0°C下反应10分钟或室温下反应1分钟时,处于最高推荐浓度的QACs对EHV-1没有杀病毒作用。氯基消毒剂在-10°C下反应10分钟或室温下反应30秒时可实现对EHV-1的消毒。在5%胎牛血清存在的情况下,QACs(除苯扎氯铵外)比氯基消毒剂表现出更稳定的杀病毒效果。阴离子表面活性剂的杀病毒效果几乎与QACs相当。

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