Nouwens Femke, Visch-Brink Evy G, Van de Sandt-Koenderman Mieke M E, Dippel Diederik W J, Koudstaal Peter J, de Lau Lonneke M L
Erasmus MC University Medical Center, Department of Neurology, Rotterdam, The Netherlands.
Expert Rev Neurother. 2015;15(8):885-93. doi: 10.1586/14737175.2015.1058161. Epub 2015 Jun 18.
Aphasia due to stroke affects communication and quality of life. Most stroke survivors with aphasia receive speech and language therapy. Although an early start of treatment is advocated in clinical practice, evidence for "The earlier, the better" in aphasia rehabilitation is weak. Hence, clinicians are faced with the dilemma of when to initiate intensive treatment: as early as possible, when most of the spontaneous recovery occurs but when patients are often ill, or later, when the patients' condition is more stabilized. Here we discuss whether aphasia outcome is affected by timing of treatment in relation to stroke onset and whether there is evidence for an optimal window of time during which language therapy should be provided. Findings from various rehabilitation research fields are discussed and combined to provide principles for future research.
中风所致失语会影响沟通和生活质量。大多数失语的中风幸存者会接受言语和语言治疗。尽管临床实践中提倡尽早开始治疗,但失语康复中“越早越好”的证据并不充分。因此,临床医生面临着何时开始强化治疗的两难境地:是尽早开始,此时大部分自发恢复会发生,但患者往往病情较重;还是稍后开始,此时患者病情更稳定。在此,我们讨论失语症的治疗效果是否受治疗时间与中风发作时间关系的影响,以及是否有证据表明存在一个最佳治疗时间窗,在此期间应提供语言治疗。我们讨论并整合了来自不同康复研究领域的发现,以提供未来研究的原则。