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高血压的患病率、知晓率、治疗情况以及社会经济变量对高血压控制的影响:ELSA-巴西研究结果

Prevalence, Awareness, Treatment and Influence of Socioeconomic Variables on Control of High Blood Pressure: Results of the ELSA-Brasil Study.

作者信息

Chor Dóra, Pinho Ribeiro Antonio Luiz, Sá Carvalho Marilia, Duncan Bruce Bartholow, Andrade Lotufo Paulo, Araújo Nobre Aline, Aquino Estela Mota Lima Leão de, Schmidt Maria Inês, Griep Rosane Härter, Molina Maria Del Carmen Bisi, Barreto Sandhi Maria, Passos Valéria Maria de Azeredo, Benseñor Isabela Judith Martins, Matos Sheila Maria Alvim, Mill José Geraldo

机构信息

Department of Epidemiology, National School of Public Health, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.

Department of Internal Medicine, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.

出版信息

PLoS One. 2015 Jun 23;10(6):e0127382. doi: 10.1371/journal.pone.0127382. eCollection 2015.

Abstract

High blood pressure (HBP) is the leading risk factor for years of life lost in Brazil. Factors associated with HBP awareness, treatment and control need to be understood better. Our aim is to estimate prevalence, awareness, and types of anti-hypertensive treatment and to investigate the association of HBP control with social position. Data of 15,103 (54% female) civil servants in six Brazilian state capitals collected at the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline (2008-2010) were used to estimate prevalence and cross-sectional association of HBP control with education, per capita family income and self-reported race, using multiple logistic regression. Blood pressure was measured by the oscillometric method. 35.8% were classified as presenting HBP; 76.8% of these used anti-hypertensive medication. Women were more aware than men (84.8% v. 75.8%) and more often using medication (83.1% v. 70.7%). Adjusted HBP prevalence was, in ascending order, Whites (30.3%), Browns (38.2%) and Blacks (49.3%). The therapeutic schemes most used were angiotensin-converting enzyme inhibitors, in isolation (12.4%) or combined with diuretics (13.3%). Among those in drug treatment, controlled blood pressure was more likely in the (postgraduate) higher education group than among participants with less than secondary school education (PR = 1.21; 95% CI: 1.14-1.28), and among Asian (PR = 1.21; 95% CI: 1.12-1.32) and 'Whites (PR = 1.19; 95% CI: 1.12-1.26) compared to Blacks. Socioeconomic and racial inequality-as measured by different indicators-are strongly associated with HBP control, beyond the expected influence of health services access.

摘要

高血压是巴西寿命损失的主要风险因素。与高血压知晓、治疗和控制相关的因素需要得到更好的理解。我们的目的是估计高血压患病率、知晓率以及抗高血压治疗的类型,并调查高血压控制与社会地位之间的关联。利用巴西成人健康纵向研究(ELSA - Brasil)基线(2008 - 2010年)收集的六个巴西州首府15103名(54%为女性)公务员的数据,采用多重逻辑回归来估计高血压患病率以及高血压控制与教育程度、家庭人均收入和自我报告种族之间的横断面关联。血压通过示波法测量。35.8%的人被归类为患有高血压;其中76.8%使用抗高血压药物。女性比男性更知晓(84.8%对75.8%)且更常使用药物(83.1%对70.7%)。按升序排列,调整后的高血压患病率分别为:白人(30.3%)、棕色人种(38.2%)和黑人(49.3%)。最常用的治疗方案是血管紧张素转换酶抑制剂,单独使用(12.4%)或与利尿剂联合使用(13.3%)。在接受药物治疗的人群中,高等教育(研究生)组的血压得到控制的可能性高于初中以下学历的参与者(PR = 1.21;95%CI:1.14 - 1.28),与黑人相比,亚洲人(PR = 1.21;95%CI:1.12 - 1.32)和“白人”(PR = 1.19;95%CI:1.12 - 1.26)的血压得到控制的可能性更高。除了卫生服务可及性的预期影响外,不同指标衡量的社会经济和种族不平等与高血压控制密切相关。

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