丘脑腹后外侧核在穴位敏化现象中的作用

Function of Nucleus Ventralis Posterior Lateralis Thalami in Acupoint Sensitization Phenomena.

作者信息

Rong Pei-Jing, Zhao Jing-Jun, Yu Ling-Ling, Li Liang, Ben Hui, Li Shao-Yuan, Zhu Bing

机构信息

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie of Dongzhimen, Beijing 100700, China.

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie of Dongzhimen, Beijing 100700, China ; Wuhan Integrated TCM and Western Medicine Hospital, 215 Zhongshan Road, Qiaokou District, Wuhan, Hubei 43002, China.

出版信息

Evid Based Complement Alternat Med. 2015;2015:516851. doi: 10.1155/2015/516851. Epub 2015 Jun 16.

To observe the effect of electroacupuncture (EA) on nucleus ventralis posterior lateralis (VPL) thalami activated by visceral noxious stimulation and to explore the impact of EA on the mechanism of acupoint sensitization under a pathological state of the viscera, EA was applied at bilateral "Zusanli-Shangjuxu" acupoints. The discharge of VPL neurons was response to EA increased after colorectal distension (CRD). The stimulation at "Zusanli-Shangjuxu" acupoints enhanced discharge activity of VPL neurons under CRD-induced visceral pain. The frequency of neuronal discharge was associated with the pressure gradient of CRD which showed that visceral noxious stimulation may intensify the body's functional response to stimulation at acupoints.