视网膜内及视网膜下液的范围和位置作为视盘小凹黄斑病变患者预后的预测因素
EXTENT AND LOCATION OF INTRARETINAL AND SUBRETINAL FLUID AS PROGNOSTIC FACTORS FOR THE OUTCOME OF PATIENTS WITH OPTIC DISK PIT MACULOPATHY.
作者信息
Steel David H W, Williamson Tom H, Laidlaw D Alistair H, Sharma Priyanka, Matthews Christopher, Rees Jon, Petrou Petros, Charteris David G, Charles Stephen J, Patel C K, Crama Niels, Herbert Ed, Jackson Timothy L
机构信息
*Sunderland Eye Infirmary, Sunderland, United Kingdom; †Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom; ‡Department of Ophthalmology, St. Thomas' Hospital, London, United Kingdom; §Faculty of Applied Sciences, University of Sunderland, Sunderland, United Kingdom; ¶Moorfields Eye Hospital, London, United Kingdom; **Manchester Royal Eye Hospital, Manchester, United Kingdom; ††Oxford Eye Hospital, Oxford Radcliffe Hospitals NHS Trust, Oxford, United Kingdom; ‡‡Department of Ophthalmology, Radboud University Medical Center, Nijmegen, the Netherlands; §§Department of Ophthalmology, Musgrove Park Hospital, Taunton, United Kingdom; and ¶¶Department of Ophthalmology, School of Medicine, King's College London, London, United Kingdom.
出版信息
Retina. 2016 Jan;36(1):110-8. doi: 10.1097/IAE.0000000000000658.
PURPOSE
To determine if baseline fundoscopic and optical coherence tomography (OCT) features influence the clinical course of optic disk pit maculopathy.
METHODS
A multicenter retrospective case note review was undertaken, using standardized OCT and clinical data collection. Visual success was defined as at least a two-line visual acuity improvement, anatomical success as full resolution of OCT foveal fluid with restoration of the normal foveal contour, and partial anatomical success as incomplete resolution of the OCT foveal fluid. Outcomes were compared with a synthesis of the literature, using similar eligibility criteria.
RESULTS
Of 36 patients (36 eyes), 2 spontaneously improved and 34 underwent surgery. Visual success was achieved in 64% of surgical cases, anatomical success in 36%, and partial anatomical success in 47%. Cases with multilayer intraretinal and subretinal fluid were less likely to have visual success (P = 0.003). Cases where the fluid did not extend to the macular arcade vessels also had better visual and anatomical outcomes (P = 0.004 and 0.005, respectively).
CONCLUSION
Fundoscopic and OCT features can help predict surgical outcome in optic disk pit maculopathy.
目的
确定基线眼底镜检查和光学相干断层扫描（OCT）特征是否会影响视盘黄斑病变的临床病程。
方法
采用标准化的OCT和临床数据收集方法，进行了一项多中心回顾性病例记录审查。视力改善至少两行定义为视觉成功，OCT黄斑区液体完全消退且中央凹轮廓恢复正常定义为解剖学成功，OCT黄斑区液体未完全消退定义为部分解剖学成功。使用相似的纳入标准，将结果与文献综述进行比较。
结果
36例患者（36只眼）中，2例自发改善，34例接受了手术。手术病例中64%实现了视觉成功，36%实现了解剖学成功，47%实现了部分解剖学成功。视网膜内和视网膜下多层积液的病例视觉成功的可能性较小（P = 0.003）。液体未延伸至黄斑弓状血管的病例视觉和解剖学结果也更好（分别为P = 0.004和0.005）。
结论
眼底镜检查和OCT特征有助于预测视盘黄斑病变的手术结果。
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