墨西哥社区老年人的衰弱：11年后的故事。墨西哥健康与老龄化研究。
Frailty among Mexican community-dwelling elderly: a story told 11 years later. The Mexican Health and Aging Study.
作者信息
Aguilar-Navarro Sara G, Amieva Hélène, Gutiérrez-Robledo Luis Miguel, Avila-Funes José Alberto
机构信息
Departamento de Geriatría, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal, México.
Centre de Recherche Inserm, Université Victor Segalen Bordeaux 2, Bordeaux, France.
出版信息
Salud Publica Mex. 2015;57 Suppl 1(0 1):S62-9. doi: 10.21149/spm.v57s1.7591.
OBJECTIVE
To describe the characteristics and prognosis of subjects classified as frail in a large sample of Mexican community-dwelling elderly.
MATERIALS AND METHODS
An eleven-year longitudinal study of 5 644 old adults participating in the Mexican Health and Aging Study (MHAS). Frailty was defined by meeting at least three of the following criteria: weight loss, weakness, exhaustion, slow walking speed and low physical activity. The main outcomes were incident disability and death. Multiple covariates were used to test the prognostic value of frailty.
RESULTS
Thirty-seven percent of participants (n= 2 102) met the frailty criteria. Frail participants were significantly older, female, less educated, with more chronic disease, lower income, and poorer self-reported health status, in comparison with their non-frail counterparts. Frailty was a predictor both for disability activities of daily living and for mortality.
CONCLUSION
After a follow-up of more than ten years, the phenotype of frailty was a predictor for adverse health-related outcomes, including ADL disability and death.
目的
描述墨西哥社区居住老年人的一个大样本中被归类为虚弱的受试者的特征和预后。
材料与方法
对参与墨西哥健康与老龄化研究（MHAS）的5644名老年人进行了为期11年的纵向研究。虚弱的定义为至少符合以下标准中的三条：体重减轻、虚弱、疲惫、步行速度缓慢和身体活动水平低。主要结局为发生残疾和死亡。使用多个协变量来检验虚弱的预后价值。
结果
37%的参与者（n = 2102）符合虚弱标准。与非虚弱的同龄人相比，虚弱的参与者年龄显著更大、为女性、受教育程度更低、患有更多慢性病、收入更低且自我报告的健康状况更差。虚弱是日常生活活动残疾和死亡率的一个预测因素。
结论
经过十多年的随访，虚弱表型是包括日常生活活动残疾和死亡在内的不良健康相关结局的一个预测因素。
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