较高的等效球镜屈光不正与角膜塑形术延缓眼轴伸长有关。
Higher spherical equivalent refractive errors is associated with slower axial elongation wearing orthokeratology.
作者信息
Fu Ai-Cun, Chen Xing-Lin, Lv Yong, Wang Shu-Lin, Shang Li-Na, Li Xiu-Hong, Zhu Yu
机构信息
The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Road, Zhengzhou, China.
Key Laboratory of Geriatrics of Health Ministry, Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
出版信息
Cont Lens Anterior Eye. 2016 Feb;39(1):62-6. doi: 10.1016/j.clae.2015.07.006. Epub 2015 Aug 4.
PURPOSE
To investigate the relationship between axial length (AL) increase and baseline spherical equivalent refractive errors (SER) in myopic children wearing orthokeratology contact lenses (OK).
METHODS
One hundred fifteen Chinese (115 right eyes) children wearing OK were enrolled in this cohort study. Gender, age, baseline SER, corneal power, corneal astigmatism, and AL at baseline and 2 years after wearing OK were collected. Univariate analysis and trend test were used to estimate the relationship between change in AL and baseline SER.
RESULTS
After univariate analysis, a statistically significant relationship was found between change in AL and baseline SER (β=0.061, 95% CI: 0.015-0.111, P=0.015). In the trend test, after adjusting for potential confounders, higher SER was associated with smaller increases in AL (P trend=0.041).
CONCLUSIONS
The SER at baseline was associated with AL growth in myopic children wearing OK. The higher SER was associated with slower AL growth and control the development of myopia.
目的
探讨佩戴角膜塑形术隐形眼镜（OK镜）的近视儿童眼轴长度（AL）增加与基线等效球镜屈光不正（SER）之间的关系。
方法
本队列研究纳入了115名佩戴OK镜的中国儿童（115只右眼）。收集了性别、年龄、基线SER、角膜屈光力、角膜散光以及佩戴OK镜基线时和2年后的AL。采用单因素分析和趋势检验来评估AL变化与基线SER之间的关系。
结果
单因素分析后，发现AL变化与基线SER之间存在统计学显著关系（β=0.061，95%CI：0.015-0.111，P=0.015）。在趋势检验中，在调整潜在混杂因素后，较高的SER与AL较小的增加相关（P趋势=0.041）。
结论
佩戴OK镜的近视儿童基线时的SER与AL增长有关。较高的SER与较慢的AL增长相关，并可控制近视的发展。
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