Wang Anken, Zang Wansheng, Shen Li, Gao Lu, Yang Chenhao
Children's hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Heliyon. 2024 Mar 11;10(6):e27562. doi: 10.1016/j.heliyon.2024.e27562. eCollection 2024 Mar 30.
To determine the differences in myopia control efficiency and corneal reshaping between three different brands of orthokeratology (OK) lenses (Lucid, Euclid, and Alpha).
We retrospectively reviewed subjects who started simultaneously using different brands of OK lenses. For each participant, every 6 months in the 19 months of following, the changes in axial length (AL), horizontal and vertical maximum distances of the treatment zone (HMDTZ and VMDTZ), width of the high convex zone (WHCZ), distance of decentration, and horizontal and vertical components of the decentration vector were measured. The average values of the above data, the average value of the decentration vector (ADV), and the average value of decentration calculated algebraically (ADA) were calculated.
All the three pairs (Lucid (n = 46) vs. Euclid (n = 46): groups Lucid-versus-Euclid-Lucid (LE-L) and LE-E), Lucid (n = 50) vs. Alpha (n = 50): groups LA-L and LA-A), and Euclid (n = 17) vs. Alpha (n = 17): groups EA-E and EA-A) showed good comparability. Regarding the change in AL during 19 months, none of the pairs showed significant differences (LE-L:0.27 ± 0.24 mm, LE-E:0.31 ± 0.24 mm ( = 0.68); LA-L:0.36 ± 0.26 mm, LA-A:0.36 ± 0.27 mm ( = 0.85); EA-E:0.34 ± 0.27 mm, EA-A:0.41 ± 0.28 mm ( = 0.63)). Regarding treatment zone, Lucid showed the largest HMDTZ and VMDTZ (both < 0.05). Regarding the WHCZ, none of the pairs showed significant differences. For the ADV and ADA, Lucid had more ADV and ADA than Euclid (ADV: LE-L:0.73 ± 0.44 mm, LE-E:0.55 ± 0.45 mm, < 0.05; ADA: LE-L:0.80 ± 0.41 mm, LE-E:0.63 ± 0.44 mm, < 0.05), and the remaining pairs showed no significant difference. For the overall cohort with 113 eyes, the change in AL was weakly correlated with both ADV and ADA (both < 0.05). Regarding the ADV/ADA, all pairs showed no significant differences, indicating equal lens position stability.
After OK, there were no significant differences between the different pairs of the three brands in AL growth, WHCZ, or lens position stability, although Lucid had a larger treatment zone than Euclid and Alpha, and Lucid had more decentration than Euclid. A larger lens decentration were weakly related to less AL growth.
确定三种不同品牌的角膜塑形术(OK)镜片(Lucid、Euclid和Alpha)在控制近视效率和角膜重塑方面的差异。
我们回顾性研究了同时开始使用不同品牌OK镜片的受试者。对于每位参与者,在随后的19个月中,每6个月测量一次眼轴长度(AL)、治疗区水平和垂直最大距离(HMDTZ和VMDTZ)、高凸区宽度(WHCZ)、偏心距离以及偏心向量的水平和垂直分量的变化。计算上述数据的平均值、偏心向量平均值(ADV)以及代数计算的偏心平均值(ADA)。
所有三对(Lucid(n = 46)与Euclid(n = 46):Lucid与Euclid - Lucid组(LE - L)和LE - E组)、Lucid(n = 50)与Alpha(n = 50):LA - L组和LA - A组)、Euclid(n = 17)与Alpha(n = 17):EA - E组和EA - A组)均具有良好的可比性。关于19个月期间AL的变化,各对之间均无显著差异(LE - L:0.27±0.24mm,LE - E:0.31±0.24mm(P = 0.68);LA - L:0.36±0.26mm,LA - A:0.36±0.27mm(P = 0.85);EA - E:0.34±0.27mm,EA - A:0.41±0.28mm(P = 0.63))。关于治疗区,Lucid的HMDTZ和VMDTZ最大(均P < 0.05)。关于WHCZ,各对之间均无显著差异。对于ADV和ADA,Lucid的ADV和ADA高于Euclid(ADV:LE - L:0.73±0.44mm,LE - E:0.55±0.45mm,P < 0.05;ADA:LE - L:0.80±0.41mm,LE - E:0.63±0.44mm,P < 0.05),其余各对无显著差异。对于113只眼的总体队列,AL的变化与ADV和ADA均呈弱相关(均P < 0.05)。关于ADV/ADA,各对均无显著差异,表明镜片位置稳定性相同。
角膜塑形术后,三个品牌不同对之间在AL增长、WHCZ或镜片位置稳定性方面无显著差异,尽管Lucid的治疗区比Euclid和Alpha大,且Lucid的偏心比Euclid多。较大的镜片偏心与较少的AL增长呈弱相关。