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参与异黄酮代谢的肠道细菌对（-）-表儿茶素、（+）-表儿茶素、（-）-儿茶素和（+）-儿茶素的生物转化作用。

Biotransformation of (-)-epicatechin, (+)-epicatechin, (-)-catechin, and (+)-catechin by intestinal bacteria involved in isoflavone metabolism.

作者信息

Takagaki Akiko, Nanjo Fumio

机构信息

a Food Research Laboratories , Mitsui Norin Co., Ltd. , Fujieda , Japan.

出版信息

Biosci Biotechnol Biochem. 2016;80(1):199-202. doi: 10.1080/09168451.2015.1079480. Epub 2015 Aug 27.

DOI:10.1080/09168451.2015.1079480
PMID:26312950
Abstract

Isoflavone-metabolizing bacteria, Adlercreutzia equolifaciens, Asaccharobacter celatus, Slackia equolifaciens, and Slackia isoflavoniconvertens catalyzed C-ring cleavage of (-)-epicatechin and (+)-catechin, (+)-epicatechin, and (-)-catechin in varying degrees. The cleaving abilities of (-)-epicatechin and (+)-catechin were enhanced by hydrogen, except (+)-catechin cleavage by S. equolifaciens, which was not accelerated. (-)-Catechin cleavage by Ad. equolifaciens was remarkably accelerated by hydrogen.

摘要

异黄酮代谢细菌，马尿酸阿德勒克雷茨菌、塞氏无糖菌、马尿酸松弛菌和异黄酮转化松弛菌对（-）-表儿茶素、（+）-儿茶素、（+）-表儿茶素和（-）-儿茶素的C环裂解具有不同程度的催化作用。氢气可增强（-）-表儿茶素和（+）-儿茶素的裂解能力，但马尿酸松弛菌对（+）-儿茶素的裂解不受氢气加速。马尿酸阿德勒克雷茨菌对（-）-儿茶素的裂解在氢气作用下显著加速。

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